Extramammary Paget's disease (patient information)

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What is extramammary Paget's disease?

Extramamary Paget's disease is first reported by Dr. Radcliffe Crocker in 1889. This disease is eczematoid changes in the skin of vulva, penis, greater lip of pudendum and crissum, etc. Usual symptoms include redness, tingling, itching, increased sensitivity, burning, and pain of the skin. Treatments involve surgery, radiation therapy, or a combination of them.

How do I know if I have extramammary Paget's disease and what are the symptoms of extramammary Paget's disease?

Usual signs and symptoms are:

• Eczematoid changes in the area skin

• Tingling, itching, increased sensitivity, burning, and pain of the skin

Other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that the problems can be diagnosed and treated as early as possible.

Who is at risk for extramammary Paget's disease?

The cause of Extramammary Paget's disease (EMPD) is unknown.

How to know you have extramammary Paget's disease?

• Biopsy: Biopsy is the most important test for the diagnosis. During this peroid, the doctors remove a small amount of tissue for examination under a microscope. Then the pathologists may analyze the samples and tell whether the tissues is benign or cancerous, what kind of cancer it is.

When to seek urgent medical care?

Call your health care provider if symptoms of extramammary Paget's disease develop. If you experience either of the following symptoms, seeking urgent medical care as soon as possible:

• Skin irritation, redness or scaliness of the skin

Treatment options

Patients with extramammary Paget's disease have many treatment options. The selection depends on the stage of the tumor. The options are surgery, radiation therapy, or a combination of these methods. Before treatment starts, ask your health care team about possible side effects and how treatment may change your normal activities. Because cancer treatments often damage healthy cells and tissues, side effects are common. Side effects may not be the same for each person, and they may change from one treatment session to the next.

• Surgery: This is the main treatment for the disease. The goal is to remove the tumor and some surrounding tissue to make sure that the entire tumor is removed. The indication of surgery depends on the stage of the cancer and the patient's general health.

• Radiation therapy: This is a cancer treatment to kill cancer cells or keep them from growing by using high-energy x-rays or other types of radiation.

Diseases with similar symptoms

• Basal Cell Carcinoma

• Intertrigo

• Lichen simplex chronicus

• Candidiasis

• Contact Dermatitis

• Tinea Cruris

Where to find medical care for extramammary Paget's disease?

Directions to Hospitals Treating extramammary Paget's disease

Prevention of extramammary Paget's disease

For the risk factors are not clear, the preventive measure is unknown.

What to expect (Outook/Prognosis)?

The prognosis of extramamary Paget's disease depends on the following:

• Whether or not the tumor can be removed by surgery

• The stage of the cancer: the size of the tumor, whether the cancer has spread outside the vulva or penis

• The patient’s general health

• Whether the cancer has just been diagnosed or has recurred

Copyleft Sources

http://dermnetnz.org/site-age-specific/extra-mammary-paget.html

http://emedicine.medscape.com/article/1100397-overview