Autoimmune polyendocrine syndrome (patient information)

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Overview of autoimmune polyendocrine syndrome?

Autoimmune polyendocrine syndrome ia a rare disease that consists of multiple endocrine gland insufficiencies. There are three autoimmune polyendocrine syndromes: type I, II and III. Type I and type II are also known as Schmidt syndrome. Type III often occurs in adults.

Autoimmune polyendocrine syndrome type I

Autoimmune polyendocrine syndrome, type I, is a very rare disorder. Studies demonstrate that congenital rubella infections and genetic mutations may play an important role in the cause of autoimmune polyendocrine syndrome type I. The three major clinical features of autoimmune polyendocrine syndrome, type I, are chronic mucocutaneous candidiasis, hypoparathyroidism, and autoimmune adrenal insufficiency. Patients with autoimmune polyendocrine syndrome type I ususally appear candidiasis before five years old as the first clinical manifestation. The next signs may be hypoparathyroidism, usually in people younger than 10 years. Lastly, autoimmune adrenal insufficiency occurs in people younger than 15 years. Other manifestations include type I diabetes, hypogonadism, pernicious anemia, malabsorption, alopecia, and vitiligo.

Where to find medical care for autoimmune polyendocrine syndrome?

Directions to Hospitals Treating autoimmune polyendocrine syndrome

Copyleft Sources

http://emedicine.medscape.com/article/124183-overview

http://www.ist-world.org/ProjectDetails.aspx?ProjectId=832cd17eb7874b09a69201ce60c6efda

http://www.statemaster.com/encyclopedia/Autoimmune-polyendocrine-syndrome