BASDAI: Difference between revisions
No edit summary |
|||
| Line 5: | Line 5: | ||
The '''BASDAI''' is important because it is a [[validated]] diagnostic test which allows a physician (usually a [[rheumatologist]]) to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of [[ankylosing spondylitis]]. The BASDAI consists of a one through 10 scale (one being no problem and 10 being the worst problem) in response to 6 questions pertaining to the 5 major symptoms of AS: | The '''BASDAI''' is important because it is a [[validated]] diagnostic test which allows a physician (usually a [[rheumatologist]]) to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of [[ankylosing spondylitis]]. The BASDAI consists of a one through 10 scale (one being no problem and 10 being the worst problem) in response to 6 questions pertaining to the 5 major symptoms of AS: | ||
Fatigue | *Fatigue | ||
Spinal pain | *Spinal pain | ||
Joint pain / swelling | *Joint pain / swelling | ||
Areas of localized tenderness (also called [[enthesitis]], or inflammation of [[tendons]] and ligaments) | *Areas of localized tenderness (also called [[enthesitis]], or inflammation of [[tendons]] and ligaments) | ||
Morning stiffness duration | *Morning stiffness duration | ||
Morning stiffness severity | *Morning stiffness severity | ||
To give each symptom equal weighting, the average of the two scores relating to morning stiffness is taken. The resulting 0 to 50 score is divided by 5 to give a final 0 – 10 BASDAI score. Scores of 4 or greater suggest suboptimal control of disease, and patients with scores of 4 or greater are usually good candidates for either a change in their medical therapy, eligible for treatment with powerful biologic therapies such as [[etanercept]], [[infliximab]] and [[adalimumab]], or may be eligible for enrollment in clinical trials evaluating new drug therapies directed at Ankylosing Spondylitis. | To give each symptom equal weighting, the average of the two scores relating to morning stiffness is taken. The resulting 0 to 50 score is divided by 5 to give a final 0 – 10 BASDAI score. Scores of 4 or greater suggest suboptimal control of disease, and patients with scores of 4 or greater are usually good candidates for either a change in their medical therapy, eligible for treatment with powerful biologic therapies such as [[etanercept]], [[infliximab]] and [[adalimumab]], or may be eligible for enrollment in clinical trials evaluating new drug therapies directed at Ankylosing Spondylitis. | ||
== History == | == History == | ||
Revision as of 17:28, 25 January 2010
|
WikiDoc Resources for BASDAI |
|
Articles |
|---|
|
Media |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on BASDAI at Clinical Trials.gov Clinical Trials on BASDAI at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on BASDAI
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Directions to Hospitals Treating BASDAI Risk calculators and risk factors for BASDAI
|
|
Healthcare Provider Resources |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
The BASDAI is important because it is a validated diagnostic test which allows a physician (usually a rheumatologist) to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of ankylosing spondylitis. The BASDAI consists of a one through 10 scale (one being no problem and 10 being the worst problem) in response to 6 questions pertaining to the 5 major symptoms of AS:
- Fatigue
- Spinal pain
- Joint pain / swelling
- Areas of localized tenderness (also called enthesitis, or inflammation of tendons and ligaments)
- Morning stiffness duration
- Morning stiffness severity
To give each symptom equal weighting, the average of the two scores relating to morning stiffness is taken. The resulting 0 to 50 score is divided by 5 to give a final 0 – 10 BASDAI score. Scores of 4 or greater suggest suboptimal control of disease, and patients with scores of 4 or greater are usually good candidates for either a change in their medical therapy, eligible for treatment with powerful biologic therapies such as etanercept, infliximab and adalimumab, or may be eligible for enrollment in clinical trials evaluating new drug therapies directed at Ankylosing Spondylitis.
History
Garrett and coworkers writing in the Journal of Rheumatology in December 1994 described a self-administered 6-question measurement tool which was to become the gold standard for measuring and evaluating disease activity in Ankylosing Spondylitis (AS). This validated tool is the BASDAI, or the Bath Ankylosing Spondylitis Disease Activity Index. A research team consisting of rheumatologists, physiotherapists, and research associates with a special interest in AS developed the index in Bath, England, hence the reason for "Bath" in the name.
Validation
BASDAI is a quick and simple index (taking between 30 secs and 2 mins to complete) BASDAI demonstrated statistically significant (p<0.001) reliability. BASDAI encorporates a reasonable scale. The individual symptoms and the index as a whole demonstrated good score distribution, using 95% of the scale. BASDAI demonstrates a sensitivity to change within a short period of time. Following a 3 week physiotherapy course, the BASDAI showed a significant (p=0.009) 16.4% score improvement.
Tools and references