Spinal Muscular atrophy overview: Difference between revisions
(New page: Spinal muscular atrophy is the commonest genetic cause of infant mortality. It is an autosomal recessive neuromuscular disorder caused by loss of survival motor neuron gene (SM...) |
No edit summary |
||
| Line 1: | Line 1: | ||
{{Infobox_Disease | | |||
Name = {{PAGENAME}} | | |||
Image = | | |||
Caption = | | |||
DiseasesDB = 14093 | | |||
DiseasesDB_mult = {{DiseasesDB2|32911}} {{DiseasesDB2|12315}} | | |||
ICD10 = {{ICD10|G|12||g|10}} | | |||
ICD9 = {{ICD9|335.0}}-{{ICD9|335.1}} | | |||
ICDO = | | |||
OMIM = 253300 | | |||
OMIM_mult = {{OMIM2|253550}} {{OMIM2|253400}} {{OMIM2|271150}} | | |||
MedlinePlus = | | |||
eMedicineSubj = | | |||
eMedicineTopic = | | |||
MeshID = D009134 | | |||
}} | |||
{{SI}} | |||
{{CMG}} | |||
__NOTOC__ | |||
{{Editor Help}} | |||
Spinal muscular atrophy is the commonest [[genetic]] cause of infant mortality. It is an [[autosomal recessive]] [[neuromuscular]] disorder caused by loss of survival motor neuron gene (SMN1). It is primarily a pediatrics disorder resulting from degeneration of [[anterior horn cells]] ([[lower motor neurons]]) in [[spinal cord]] and [[brain stem]] nuclei. It is characterized by progressive muscle weakness predominantly affecting the proximal muscles. Though the disease is still considered to be incurable, recent advancements in the field of molecular genetic have helped in understanding the pathogenesis and raises hope for a cure in future. | Spinal muscular atrophy is the commonest [[genetic]] cause of infant mortality. It is an [[autosomal recessive]] [[neuromuscular]] disorder caused by loss of survival motor neuron gene (SMN1). It is primarily a pediatrics disorder resulting from degeneration of [[anterior horn cells]] ([[lower motor neurons]]) in [[spinal cord]] and [[brain stem]] nuclei. It is characterized by progressive muscle weakness predominantly affecting the proximal muscles. Though the disease is still considered to be incurable, recent advancements in the field of molecular genetic have helped in understanding the pathogenesis and raises hope for a cure in future. | ||
==References== | |||
{{Reflist|2}} | |||
Revision as of 03:36, 19 June 2011
| Spinal Muscular atrophy overview | |
| ICD-10 | G12 |
|---|---|
| ICD-9 | 335.0-335.1 |
| OMIM | 253300 253550 253400 271150 |
| DiseasesDB | 14093 Template:DiseasesDB2 Template:DiseasesDB2 |
| MeSH | D009134 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Spinal muscular atrophy is the commonest genetic cause of infant mortality. It is an autosomal recessive neuromuscular disorder caused by loss of survival motor neuron gene (SMN1). It is primarily a pediatrics disorder resulting from degeneration of anterior horn cells (lower motor neurons) in spinal cord and brain stem nuclei. It is characterized by progressive muscle weakness predominantly affecting the proximal muscles. Though the disease is still considered to be incurable, recent advancements in the field of molecular genetic have helped in understanding the pathogenesis and raises hope for a cure in future.