Chronic stable angina laboratory findings: Difference between revisions

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*Fibrinogen: Elevated fibrinogen levels are associated with higher risks of coronary artery disease, but in practice, coagulation studies are not recommended.
*Fibrinogen: Elevated fibrinogen levels are associated with higher risks of coronary artery disease, but in practice, coagulation studies are not recommended.


==ACC / AHA Guidelines- Recommendations for Initial Laboratory Tests for Diagnosis (DO NOT EDIT)<ref name="Gibbons1"> Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP–ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Chronic Stable Angina). Circulation. 1999; 99: 2829–2848. PMID 10351980</ref>==
==ACC / AHA Guidelines- Recommendations for Initial Laboratory Tests for Diagnosis (DO NOT EDIT)<)<ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. PMID: [http://pubmed.gov/10351980 10351980]</ref>==
{{cquote|
{{cquote|
===Class I===
===Class I===
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'''3.''' Fasting [[lipid]] panel, including total [[cholesterol]], [[HDL cholesterol]], [[triglycerides]], and calculated [[LDL cholesterol]]. ''(Level of Evidence: C)''}}
'''3.''' Fasting [[lipid]] panel, including total [[cholesterol]], [[HDL cholesterol]], [[triglycerides]], and calculated [[LDL cholesterol]]. ''(Level of Evidence: C)''}}
==ESC Guidelines for laboratory investigation in initial assessment of stable angina (DO NOT EDIT)<ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367  }} </ref>==
{{cquote|
===Class I (in all patients)===
'''1.''' Fasting lipid profile, including [[total cholesterol]], [[LDL]], [[HDL]], and [[triglycerides]]. ''(Level of Evidence: B)''
'''2.''' Fasting [[glucose]]. ''(Level of Evidence: B)''
'''3.''' Full blood count including [[Hemoglobin]] and [[white cell count]]. ''(Level of Evidence: B)''
'''4.''' [[Creatinine]]. ''(Level of Evidence: C)''
===Class I (if specifically indicated on the basis of clinical evaluation)===
'''1.''' Markers of myocardial damage if evaluation suggests clinical instability or [[ACS]]. ''(Level of Evidence: A)''
'''2.''' Thyroid function if clinically indicated. ''(Level of Evidence: C)''
===Class IIa===
'''1.''' [[Oral glucose tolerance test]]. ''(Level of Evidence: B)''
===Class IIb===
'''1.''' Hs-[[C-reactive protein]]. ''(Level of Evidence: B)''
'''2.''' Lipoprotein a, ApoA, and ApoB . ''(Level of Evidence: B)''
'''3.''' [[Homocysteine]]. ''(Level of Evidence: B)''
'''4.''' [[HbA1c]]. ''(Level of Evidence: B)''
'''5.''' NT-[[BNP]]. ''(Level of Evidence: B)''}}
==ESC Guidelines for blood tests for routine reassessment in patients with chronic stable angina (DO NOT EDIT)<ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367  }} </ref>==
{{cquote|
===Class IIa===
'''1.''' Fasting lipid profile and fasting glucose on an annual basis. ''(Level of Evidence: C)''}}


==See Also==
==See Also==
Line 29: Line 64:


==Sources==
==Sources==
*The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina <ref name="Gibbons1"> Gibbons RJ, Chatterjee K, Daley J, et al. ACC/AHA/ACP–ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients With Chronic Stable Angina). Circulation. 1999; 99: 2829–2848. PMID 10351980</ref>
*Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology <ref name="pmid16735367">{{cite journal| author=Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F et al.| title=Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. | journal=Eur Heart J | year= 2006 | volume= 27 | issue= 11 | pages= 1341-81 | pmid=16735367 | doi=10.1093/eurheartj/ehl001 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16735367  }} </ref>
 
*The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina <ref name="pmid10351980">Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=10351980 ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina).] ''Circulation'' 99 (21):2829-48. PMID: [http://pubmed.gov/10351980 10351980]</ref>


*TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina <ref name="Gibbons2">Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, Ferguson TB Jr, Fihn SD, Fraker TD Jr, Gardin JM, O'Rourke RA, Pasternak RC, Williams SV, Gibbons RJ, Alpert JS, Antman EM, Hiratzka LF, Fuster V, Faxon DP, Gregoratos G, Jacobs AK, Smith SC Jr; American College of Cardiology; American Heart Association Task Force on Practice Guidelines. Committee on the Management of Patients With Chronic Stable Angina. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). Circulation. 2003 Jan 7; 107 (1): 149-58. PMID 12515758 </ref>
*TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina <ref name="pmid12515758">Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12515758 ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina).] ''Circulation'' 107 (1):149-58. PMID: [http://pubmed.gov/12515758 12515758]</ref>


*The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina<ref name="Fraker"> Fraker TD Jr, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, Ferguson TB Jr, Gardin JM, O'Rourke RA, Williams SV, Smith SC Jr, Jacobs AK, Adams CD, Anderson JL, Buller CE, Creager MA, Ettinger SM, Halperin JL, Hunt SA, Krumholz HM, Kushner FG, Lytle BW, Nishimura R, Page RL, Riegel B, Tarkington LG, Yancy CW; American College of Cardiology; American Heart Association; American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group. 2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina. Circulation. 2007 Dec 4; 116 (23): 2762-72. Epub 2007 Nov 12. PMID 17998462 </ref>
*The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina <ref name="pmid17998462">Fraker TD, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J et al. (2007) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=17998462 2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina.] ''Circulation'' 116 (23):2762-72. [http://dx.doi.org/10.1161/CIRCULATIONAHA.107.187930 DOI:10.1161/CIRCULATIONAHA.107.187930] PMID: [http://pubmed.gov/17998462 17998462]</ref>


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Disease state]]
[[Category: Disease state]]  
[[Category:Ischemic heart diseases]]
[[Category: Ischemic heart diseases]]
[[Category:Cardiology]]
[[Category: Cardiology]]
[[Category:Emergency medicine]]
[[Category: Emergency medicine]]


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Revision as of 03:59, 19 July 2011

Chronic stable angina Microchapters

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Chronic Stable Angina
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Differentiating Chronic Stable Angina from Acute Coronary Syndromes

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Editors-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-632-7753; Cafer Zorkun, M.D., Ph.D. [2]; Associate Editor-in-Chief: Smita Kohli, M.D.

Laboratory Tests

  • Total Cholesterol, low-density lipoprotein (LDL-C) and high-density lipoprotein cholesterol (HDL-C) measurements should be performed in all patients with suspected or documented ischemic heart disease.
  • Fasting glucose level
  • Routine hematologic tests are necessary to exclude significant anemia
  • Thyroid function tests are necessary to exclude abnormal thyroid functions, which can be associated with worsening angina.
  • Homocysteinemia has been found to be a risk factor for CAD. Folate, vitamin B12 and vitamin B6 can lower the homocysteine level. Although the therapeutic implications of lowering homocysteine levels have not been fully defined, homocysteine concentrations should be measured in patients with a strong family history of coronary disease, especially if it is not explained by traditional risk factors.
  • Fibrinogen: Elevated fibrinogen levels are associated with higher risks of coronary artery disease, but in practice, coagulation studies are not recommended.

ACC / AHA Guidelines- Recommendations for Initial Laboratory Tests for Diagnosis (DO NOT EDIT)<)[1]

“

Class I

1. Hemoglobin. (Level of Evidence: C)

2. Fasting glucose. (Level of Evidence: C)

3. Fasting lipid panel, including total cholesterol, HDL cholesterol, triglycerides, and calculated LDL cholesterol. (Level of Evidence: C)

”

ESC Guidelines for laboratory investigation in initial assessment of stable angina (DO NOT EDIT)[2]

“

Class I (in all patients)

1. Fasting lipid profile, including total cholesterol, LDL, HDL, and triglycerides. (Level of Evidence: B)

2. Fasting glucose. (Level of Evidence: B)

3. Full blood count including Hemoglobin and white cell count. (Level of Evidence: B)

4. Creatinine. (Level of Evidence: C)

Class I (if specifically indicated on the basis of clinical evaluation)

1. Markers of myocardial damage if evaluation suggests clinical instability or ACS. (Level of Evidence: A)

2. Thyroid function if clinically indicated. (Level of Evidence: C)

Class IIa

1. Oral glucose tolerance test. (Level of Evidence: B)

Class IIb

1. Hs-C-reactive protein. (Level of Evidence: B)

2. Lipoprotein a, ApoA, and ApoB . (Level of Evidence: B)

3. Homocysteine. (Level of Evidence: B)

4. HbA1c. (Level of Evidence: B)

5. NT-BNP. (Level of Evidence: B)

”

ESC Guidelines for blood tests for routine reassessment in patients with chronic stable angina (DO NOT EDIT)[2]

“

Class IIa

1. Fasting lipid profile and fasting glucose on an annual basis. (Level of Evidence: C)

”

See Also

Sources

  • Guidelines on the management of stable angina pectoris: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology [2]
  • The ACC/AHA/ACP–ASIM Guidelines for the Management of Patients With Chronic Stable Angina [1]
  • TheACC/AHA 2002 Guideline Update for the Management of Patients With Chronic Stable Angina [3]
  • The 2007 Chronic Angina Focused Update of the ACC/AHA 2002 Guidelines for the Management of Patients With Chronic Stable Angina [4]

References

  1. ↑ 1.0 1.1 Gibbons RJ, Chatterjee K, Daley J, Douglas JS, Fihn SD, Gardin JM et al. (1999) ACC/AHA/ACP-ASIM guidelines for the management of patients with chronic stable angina: executive summary and recommendations. A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on Management of Patients with Chronic Stable Angina). Circulation 99 (21):2829-48. PMID: 10351980
  2. ↑ 2.0 2.1 2.2 Fox K, Garcia MA, Ardissino D, Buszman P, Camici PG, Crea F; et al. (2006). "Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology". Eur Heart J. 27 (11): 1341–81. doi:10.1093/eurheartj/ehl001. PMID 16735367.
  3. ↑ Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS et al. (2003) ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee on the Management of Patients With Chronic Stable Angina). Circulation 107 (1):149-58. PMID: 12515758
  4. ↑ Fraker TD, Fihn SD, Gibbons RJ, Abrams J, Chatterjee K, Daley J et al. (2007) 2007 chronic angina focused update of the ACC/AHA 2002 Guidelines for the management of patients with chronic stable angina: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines Writing Group to develop the focused update of the 2002 Guidelines for the management of patients with chronic stable angina. Circulation 116 (23):2762-72. DOI:10.1161/CIRCULATIONAHA.107.187930 PMID: 17998462


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