Schwannoma: Difference between revisions
No edit summary |
|||
| Line 43: | Line 43: | ||
==Diagnosis== | ==Diagnosis== | ||
===Symptoms== | ===Symptoms=== | ||
Unilateral/asymmetric hearing loss and/or [[tinnitus]] and loss of balance/[[dizziness]] are early signs of a vestibular schwannoma. Unfortunately, early detection of the tumor is sometimes difficult because the symptoms may be subtle and may not appear in the beginning stages of growth. Also, [[hearing loss]], [[dizziness]], and [[tinnitus]] are common symptoms of many middle and inner ear problems (the important point here is that unilateral or asymmetric symptoms are the worrisome ones). Once the symptoms appear, a thorough ear examination and hearing test ([[audiogram]]) are essential for proper diagnosis. Computerized tomography (CT) scans, enhanced with intravenous dye (contrast), and magnetic resonance imaging (MRI) are critical in the early detection of a vestibular schwannoma and are helpful in determining the location and size of a tumor and in planning its microsurgical removal. | Unilateral/asymmetric hearing loss and/or [[tinnitus]] and loss of balance/[[dizziness]] are early signs of a vestibular schwannoma. Unfortunately, early detection of the tumor is sometimes difficult because the symptoms may be subtle and may not appear in the beginning stages of growth. Also, [[hearing loss]], [[dizziness]], and [[tinnitus]] are common symptoms of many middle and inner ear problems (the important point here is that unilateral or asymmetric symptoms are the worrisome ones). | ||
===Audiogram=== | |||
Once the symptoms appear, a thorough ear examination and hearing test ([[audiogram]]) are essential for proper diagnosis. | |||
===Imaging Studies=== | |||
Computerized tomography (CT) scans, enhanced with intravenous dye (contrast), and magnetic resonance imaging (MRI) are critical in the early detection of a vestibular schwannoma and are helpful in determining the location and size of a tumor and in planning its microsurgical removal. | |||
==Treatment== | ==Treatment== | ||
Revision as of 22:19, 28 July 2011
For patient information click here
| Schwannoma | |
| ICD-O: | 9560/0 |
|---|---|
| DiseasesDB | 33713 |
| MeSH | D009442 |
|
WikiDoc Resources for Schwannoma |
|
Articles |
|---|
|
Most recent articles on Schwannoma |
|
Media |
|
Evidence Based Medicine |
|
Clinical Trials |
|
Ongoing Trials on Schwannoma at Clinical Trials.gov Clinical Trials on Schwannoma at Google
|
|
Guidelines / Policies / Govt |
|
US National Guidelines Clearinghouse on Schwannoma
|
|
Books |
|
News |
|
Commentary |
|
Definitions |
|
Patient Resources / Community |
|
Patient resources on Schwannoma Discussion groups on Schwannoma Patient Handouts on Schwannoma Directions to Hospitals Treating Schwannoma Risk calculators and risk factors for Schwannoma
|
|
Healthcare Provider Resources |
|
Causes & Risk Factors for Schwannoma |
|
Continuing Medical Education (CME) |
|
International |
|
|
|
Business |
|
Experimental / Informatics |
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Synonyms and keywords: Acoustic neuroma, acoustic neurinoma, or acoustic neurilemoma, neurilemmoma, neurinoma, neurolemmoma, Schwann cell tumor
Overview
A schwannoma is a kind of tumor originating from the Schwann cells. The insulating myelin sheath which covers peripheral nerves is produced by the Schwann cells. Hence, one kind of tumor originating from the Schwann cells is called a schwannoma.
Schwannomas are very homogenous tumors consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant degenerating into a form of cancer known as neurofibrosarcoma.
Schwannomas can arise from a genetic disorder called neurofibromatosis. They are universally S-100 positive.
Schwannomas can arise from a genetic disorder called schwannomatosis.
Pathophysiology
Microscopic Pathology
-
Subcutaneous schwannoma
.JPG){kind=link}
_Antoni_B.jpg){kind=link}
_Antoni_B.jpg){kind=link}
_Antoni_B.jpg){kind=link}
_S-100_immunostain.jpg){kind=link}
Diagnosis
Symptoms
Unilateral/asymmetric hearing loss and/or tinnitus and loss of balance/dizziness are early signs of a vestibular schwannoma. Unfortunately, early detection of the tumor is sometimes difficult because the symptoms may be subtle and may not appear in the beginning stages of growth. Also, hearing loss, dizziness, and tinnitus are common symptoms of many middle and inner ear problems (the important point here is that unilateral or asymmetric symptoms are the worrisome ones).
Audiogram
Once the symptoms appear, a thorough ear examination and hearing test (audiogram) are essential for proper diagnosis.
Imaging Studies
Computerized tomography (CT) scans, enhanced with intravenous dye (contrast), and magnetic resonance imaging (MRI) are critical in the early detection of a vestibular schwannoma and are helpful in determining the location and size of a tumor and in planning its microsurgical removal.
Treatment
Schwannomas can be removed surgically, but they can then recur.
References
<Reflist|2>
See also
- Neurofibroma
- Vestibular schwannoma (Acoustic neuroma)
Template:Nervous tissue tumors
cs:Neurinom de:Schwannom fa:شوانوما it:Schwannoma it:Schwannoma