Hyperpituitarism: Difference between revisions
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==Overview== | |||
'''Hyperpituitarism''' is the result of excess secretion of adenohypophyseal trophic [[hormones]] most commonly by a functional [[pituitary adenoma]]. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders. | '''Hyperpituitarism''' is the result of excess secretion of adenohypophyseal trophic [[hormones]] most commonly by a functional [[pituitary adenoma]]. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders. | ||
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Revision as of 14:12, 2 August 2011
For patient information click here
| Hyperpituitarism | |
| ICD-10 | E22 |
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| ICD-9 | 253.1 |
| MeSH | D006964 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Hyperpituitarism is the result of excess secretion of adenohypophyseal trophic hormones most commonly by a functional pituitary adenoma. Other causes are hyperplasias and carcinomas of the adenohypophysis, secretion by non-pituitary tumours and certain hypothalamic disorders.
Clinical manifestations
Depending on the cell type(s) affected, clinical manifestations of hormone excess may include:
- Hyperprolactinaemia
- Cushing's disease
- Precocious puberty
- Gigantism or Acromegaly
- Hyperthyroidism (rare)
Associated conditions
When there is an enlargement of the pituitary tissue, hyperpituitarism is often associated with:
- Visual field defects, classically bitemporal hemianopia
- Radiographic abnormalities of the sella turcica, such as sellar expansion, bony erosion and disuption of the diaphragma sellae
- Increased intracranial pressure
Symptoms
Symptoms caused by hormone excess and associated mass effects include:
- Headache
- Visual field loss or Double vision
- Excessive sweating
- Hoarseness
- Milk secretion from breast
- Sleep apnea
- Carpal tunnel syndrome
- Joint pain and limitation of motion
- Muscle weakness
- Numbness or tingling of skin