Asthma and gastroesophageal reflux: Difference between revisions
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==Overview== | ==Overview== | ||
The underlying [[GERD|gastro-esophageal reflux disease]] predisposes the patient to have repetitive episodes of acid aspiration, which subsequently causes repeated airway inflammation and results in '''irritant-induced''' asthma.<ref name="pmid19157219">Cuevas Hernández MM, Arias Hernández RM (2008) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=19157219 [Pulmonary gammagraphy study in asthmatic children with gastroesophageal reflux].] ''Rev Alerg Mex'' 55 (6):229-33. PMID: [http://pubmed.gov/19157219 19157219]</ref><ref name="pmid6142759">Shapiro GG, Christie DL (1983) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=6142759 Gastroesophageal reflux and asthma.] ''Clin Rev Allergy'' 1 (1):39-56. PMID: [http://pubmed.gov/6142759 6142759]</ref> The incidence of GERD in patients with asthma is approximately 38%. Asthmatics resistant to therapy are commonly associated with GERD, but identification and treatment of GERD has not shown to relate to the improvement in asthmatic control.<ref name="pmid15821199">Leggett JJ, Johnston BT, Mills M, Gamble J, Heaney LG (2005) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=15821199 Prevalence of gastroesophageal reflux in difficult asthma: relationship to asthma outcome.] ''Chest'' 127 (4):1227-31. [http://dx.doi.org/10.1378/chest.127.4.1227 DOI:10.1378/chest.127.4.1227] PMID: [http://pubmed.gov/15821199 15821199]</ref> | |||
==References== | ==References== | ||
Revision as of 18:33, 23 September 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The underlying gastro-esophageal reflux disease predisposes the patient to have repetitive episodes of acid aspiration, which subsequently causes repeated airway inflammation and results in irritant-induced asthma.[1][2] The incidence of GERD in patients with asthma is approximately 38%. Asthmatics resistant to therapy are commonly associated with GERD, but identification and treatment of GERD has not shown to relate to the improvement in asthmatic control.[3]
References
- ↑ Cuevas Hernández MM, Arias Hernández RM (2008) [Pulmonary gammagraphy study in asthmatic children with gastroesophageal reflux.] Rev Alerg Mex 55 (6):229-33. PMID: 19157219
- ↑ Shapiro GG, Christie DL (1983) Gastroesophageal reflux and asthma. Clin Rev Allergy 1 (1):39-56. PMID: 6142759
- ↑ Leggett JJ, Johnston BT, Mills M, Gamble J, Heaney LG (2005) Prevalence of gastroesophageal reflux in difficult asthma: relationship to asthma outcome. Chest 127 (4):1227-31. DOI:10.1378/chest.127.4.1227 PMID: 15821199