Nocturnal asthma: Difference between revisions
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==Overview== | ==Overview== | ||
Nocturnal worsening of asthma is very common finding in asthmatics. The pathophysiology of nocturnal asthma is closely associated with the chronobiology and the science of biologic processes that have time-related rhythms. Hence, understanding the circadian rhythm is important to interpret the changes in pulmonary function that occurs in sleeping asthmatics. A large population based study reported dyspneic episodes without therapy in asthmatics occurred between 10 P.M. and 7 A.M.<ref name="pmid8494197">Martin RJ (1993) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8494197 Nocturnal asthma: circadian rhythms and therapeutic interventions.] ''Am Rev Respir Dis'' 147 (6 Pt 2):S25-8. PMID: [http://pubmed.gov/8494197 8494197]</ref> Another population based survey that assessed 7729 patients, reported approximate 74% patients woke-up at least once a week with symptoms, 64% woke-up three times per week and 39% patients woke-up every night with symptoms.<ref name="pmid3400687">Turner-Warwick M (1988) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=3400687 Epidemiology of nocturnal asthma.] ''Am J Med'' 85 (1B):6-8. PMID: [http://pubmed.gov/3400687 3400687]</ref> | Nocturnal worsening of asthma is very common finding in asthmatics. The pathophysiology of nocturnal asthma is closely associated with the chronobiology and the science of biologic processes that have time-related rhythms. Hence, understanding the circadian rhythm is important to interpret the changes in pulmonary function that occurs in sleeping asthmatics. A large population based study reported dyspneic episodes without therapy in asthmatics occurred between 10 P.M. and 7 A.M.<ref name="pmid8494197">Martin RJ (1993) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=8494197 Nocturnal asthma: circadian rhythms and therapeutic interventions.] ''Am Rev Respir Dis'' 147 (6 Pt 2):S25-8. PMID: [http://pubmed.gov/8494197 8494197]</ref> Another population based survey that assessed 7729 patients, reported approximate 74% patients woke-up at least once a week with symptoms, 64% woke-up three times per week and 39% patients woke-up every night with symptoms.<ref name="pmid3400687">Turner-Warwick M (1988) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=3400687 Epidemiology of nocturnal asthma.] ''Am J Med'' 85 (1B):6-8. PMID: [http://pubmed.gov/3400687 3400687]</ref> | ||
==Asthma and sleep apnea== | |||
It is recognized with increasing frequency, that patients who have both [[obstructive sleep apnea]] and [[bronchial asthma]], often improve tremendously when the sleep apnea is diagnosed and treated.<ref name=sleep_anpea1>{{cite press release | title = Breathing disorders during sleep are common among asthmatics, may help predict severe asthma | publisher = University of Michigan Health System | date = May 25, 2005 | url = http://www.med.umich.edu/opm/newspage/2005/asthmasleep.htm }}</ref><ref name="pmid18849401">Teodorescu M, Consens FB, Bria WF, Coffey MJ, McMorris MS, Weatherwax KJ et al. (2009) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=18849401 Predictors of habitual snoring and obstructive sleep apnea risk in patients with asthma.] ''Chest'' 135 (5):1125-32. [http://dx.doi.org/10.1378/chest.08-1273 DOI:10.1378/chest.08-1273] PMID: [http://pubmed.gov/18849401 18849401]</ref> However, [[CPAP]] has not shown to be effective in patients with nocturnal asthma alone.<ref name=CPAP_not_an_anti-asthmatic>{{cite web | url = http://www.sleepapnea.org/resources/pubs/asthma-osa.html | title = Asthma and OSA | accessmonthday = September 23 | accessyear = 2006 | last = Basner | first = Robert C. | work = ASAA Resources > Publications | publisher = American Sleep Apnea Association}}</ref> | |||
==References== | ==References== | ||
Revision as of 18:56, 23 September 2011
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Nocturnal asthma On the Web |
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American Roentgen Ray Society Images of Nocturnal asthma |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]
Overview
Nocturnal worsening of asthma is very common finding in asthmatics. The pathophysiology of nocturnal asthma is closely associated with the chronobiology and the science of biologic processes that have time-related rhythms. Hence, understanding the circadian rhythm is important to interpret the changes in pulmonary function that occurs in sleeping asthmatics. A large population based study reported dyspneic episodes without therapy in asthmatics occurred between 10 P.M. and 7 A.M.[1] Another population based survey that assessed 7729 patients, reported approximate 74% patients woke-up at least once a week with symptoms, 64% woke-up three times per week and 39% patients woke-up every night with symptoms.[2]
Asthma and sleep apnea
It is recognized with increasing frequency, that patients who have both obstructive sleep apnea and bronchial asthma, often improve tremendously when the sleep apnea is diagnosed and treated.[3][4] However, CPAP has not shown to be effective in patients with nocturnal asthma alone.[5]
References
- ↑ Martin RJ (1993) Nocturnal asthma: circadian rhythms and therapeutic interventions. Am Rev Respir Dis 147 (6 Pt 2):S25-8. PMID: 8494197
- ↑ Turner-Warwick M (1988) Epidemiology of nocturnal asthma. Am J Med 85 (1B):6-8. PMID: 3400687
- ↑ "Breathing disorders during sleep are common among asthmatics, may help predict severe asthma" (Press release). University of Michigan Health System. May 25, 2005.
- ↑ Teodorescu M, Consens FB, Bria WF, Coffey MJ, McMorris MS, Weatherwax KJ et al. (2009) Predictors of habitual snoring and obstructive sleep apnea risk in patients with asthma. Chest 135 (5):1125-32. DOI:10.1378/chest.08-1273 PMID: 18849401
- ↑ Basner, Robert C. "Asthma and OSA". ASAA Resources > Publications. American Sleep Apnea Association. Unknown parameter
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