Status asthmaticus: Difference between revisions

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===Physical Examination===
===Physical Examination===
====Vital Signs====
====Vital Signs====
*Early stages:
*[[Tachypnea|Increased respiratory rate]] greater than 30 cycles per minute
:*[[Tachypnea|Increased respiratory rate]] greater than 30 cycles per minute
*[[Tachycardia|Increased heart rate]]
:*[[Tachycardia|Increased heart rate]]
*[[Pulsus paradoxus]] (is a fall in [[Systolic blood pressure|SBP]] greater than 20-40 mmHg during inspiration)
:*[[Pulsus paradoxus]] (a fall of SBP greater than 20-40 mmHg during inspiration)
 
*With progressive untreated airway obstruction, increased work of breathing may result in [[bradycardia]], [[hypoventilation]] and [[cardiorespiratory arrest]]
   
   
====General Physical Examination====
====General Physical Examination====
*Sit upright with arms extended to support the upper chest ('''tripod position''') that assist the use of accessory muscles of respiration
*Sit upright with arms extended to support the upper chest ('''tripod position''') that assist the use of accessory muscles of respiration
*Use of accessory muscles of respiration
*[[Asthma pulmonary function test#Peak Expiratory Flow Rate|Peak flow rate]] is a simple bedside measurement of airway obstruction and a red zone indicates less than 50% of the usual or normal peak flow reading signifying severe airway obstruction.
 
====Respiratory Examination====
=====Inspection=====
*Use of accessory muscles of respiration correlates with the disease severity
*Intercostal retractions
*Paradoxical thoraco-abdominal breathing
 
=====Auscultation=====
*High-pitch prolong polyphonic expiratory [[wheeze]]
*Bilateral crackles
*Air entry may or may not be reduced depending on the severity
*Absence of [[wheeze]], breath sounds secondary to severe airway obstruction may represent a silent chest which is an ominous sign of imminent [[respiratory failure]].
 
====Cardiovascular Examination====
Progressive untreated airway obstruction and increased work of breathing eventually leads to worsening [[hypoxemia]], [[hypercarbia]] and increased [[air trapping]] with compromised [[stroke volume]] that results in [[bradycardia]], [[hypotension]], [[hypoventilation]] and subsequent [[cardiorespiratory arrest]].
 
====Neurological Examination====
*Level of consciousness ranges from lethargy, agitation to even [[loss of consciousness]] or [[seizure]], secondary to severe airway obstruction, [[hypoxia]] and carbon-di-oxide retention.
*Unable to speak in full sentences


==References==
==References==

Revision as of 03:30, 27 September 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

Status asthmaticus is an acute exacerbation of asthma that does not respond to standard bronchodilator and corticosteroid therapy. Symptoms include chest tightness, rapidly progressive dyspnea, non-productive cough and wheezing. Status asthmaticus if left untreated may result in severe bronchospasm, mucus plugging and rapidly develops acidosis and respiratory failure as a consequent of carbon di oxide retention and hypoxemia.

Epidemiology

Approximately 10% of the US population is affected by asthma with status asthmaticus requiring highest rates of hospitalization.[1]

Predisposing factors

  • Increase use of bronchodilator despite resistance,
  • Frequent exacerbations despite the use of corticosteroids,
  • Despite adhering to therapy, a peak flow rate of less than 10% from baseline,
  • Frequent hospitalization for acute attacks,
  • History of syncope or seizure during an acute asthmatic attack,
  • Oxygen saturation lower than 92% despite supplemental oxygen,
  • Airway obstruction is significantly reduced, resulting in severe impairment of air motion that leads to a silent chest with the absence of wheeze suggestive of an imminent respiratory arrest.

Diagnosis

History and Symptoms

Physical Examination

Vital Signs

General Physical Examination

  • Sit upright with arms extended to support the upper chest (tripod position) that assist the use of accessory muscles of respiration
  • Peak flow rate is a simple bedside measurement of airway obstruction and a red zone indicates less than 50% of the usual or normal peak flow reading signifying severe airway obstruction.

Respiratory Examination

Inspection
  • Use of accessory muscles of respiration correlates with the disease severity
  • Intercostal retractions
  • Paradoxical thoraco-abdominal breathing
Auscultation
  • High-pitch prolong polyphonic expiratory wheeze
  • Bilateral crackles
  • Air entry may or may not be reduced depending on the severity
  • Absence of wheeze, breath sounds secondary to severe airway obstruction may represent a silent chest which is an ominous sign of imminent respiratory failure.

Cardiovascular Examination

Progressive untreated airway obstruction and increased work of breathing eventually leads to worsening hypoxemia, hypercarbia and increased air trapping with compromised stroke volume that results in bradycardia, hypotension, hypoventilation and subsequent cardiorespiratory arrest.

Neurological Examination

  • Level of consciousness ranges from lethargy, agitation to even loss of consciousness or seizure, secondary to severe airway obstruction, hypoxia and carbon-di-oxide retention.
  • Unable to speak in full sentences

References

  1. Gorelick M, Scribano PV, Stevens MW, Schultz T, Shults J (2008) Predicting need for hospitalization in acute pediatric asthma. Pediatr Emerg Care 24 (11):735-44. DOI:10.1097/PEC.0b013e31818c268f PMID: 18955910


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