Asthma in pregnancy: Difference between revisions
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==Pathophysiology== | ==Pathophysiology== | ||
During pregnancy, due to high levels of progesterone, minute ventilatory rate is increased causing compensated [[respiratory alkalosis]]<ref name="pmid16443140">{{cite journal| author=Wise RA, Polito AJ, Krishnan V| title=Respiratory physiologic changes in pregnancy. | journal=Immunol Allergy Clin North Am | year= 2006 | volume= 26 | issue= 1 | pages= 1-12 | pmid=16443140 | doi=10.1016/j.iac.2005.10.004 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16443140 }} </ref>. Hence the [[arterial blood gases]] may reveal a higher PO<sub>2</sub> and lower PCO<sub>2</sub> with mild alkalotic PH. | During pregnancy, due to high levels of progesterone, minute ventilatory rate is increased causing compensated [[respiratory alkalosis]]<ref name="pmid16443140">{{cite journal| author=Wise RA, Polito AJ, Krishnan V| title=Respiratory physiologic changes in pregnancy. | journal=Immunol Allergy Clin North Am | year= 2006 | volume= 26 | issue= 1 | pages= 1-12 | pmid=16443140 | doi=10.1016/j.iac.2005.10.004 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16443140 }} </ref>. Hence the [[arterial blood gases]] may reveal a higher PO<sub>2</sub> and lower PCO<sub>2</sub> with mild alkalotic PH. Normal PCO<sub>2</sub> during pregnancy is suggestive of impending [[respiratory failure]]. | ||
Asthma is characterized by broncho-constriction or inflammation of airways with production of thick mucoid secretions. | |||
==References== | ==References== |
Revision as of 18:14, 27 September 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]
Overview
Asthma is one of the most common pulmonary conditions occurring during pregnancy[1] with a prevalence rate of 3.7% to 8.4% in United States during the period 1997-2001[2].
Pathophysiology
During pregnancy, due to high levels of progesterone, minute ventilatory rate is increased causing compensated respiratory alkalosis[3]. Hence the arterial blood gases may reveal a higher PO2 and lower PCO2 with mild alkalotic PH. Normal PCO2 during pregnancy is suggestive of impending respiratory failure.
Asthma is characterized by broncho-constriction or inflammation of airways with production of thick mucoid secretions.
References
- ↑ Rey E, Boulet LP (2007). "Asthma in pregnancy". BMJ. 334 (7593): 582–5. doi:10.1136/bmj.39112.717674.BE. PMC 1828355. PMID 17363831.
- ↑ Kwon HL, Belanger K, Bracken MB (2003). "Asthma prevalence among pregnant and childbearing-aged women in the United States: estimates from national health surveys". Ann Epidemiol. 13 (5): 317–24. PMID 12821270.
- ↑ Wise RA, Polito AJ, Krishnan V (2006). "Respiratory physiologic changes in pregnancy". Immunol Allergy Clin North Am. 26 (1): 1–12. doi:10.1016/j.iac.2005.10.004. PMID 16443140.