Metabolic syndrome dietary therapy: Difference between revisions
| Line 19: | Line 19: | ||
==Trial supportive data== | ==Trial supportive data== | ||
'''1)''' '''Study design''' – [[ | ===Meta-analysis on effect of Mediterranean diet on metabolic syndrome=== | ||
'''1)''' '''Study design''' – [[Meta-analysis]] {50 original research studies (35 clinical trials, 2 prospective and 13 cross-sectional), with 534,906 participants, were included in the analysis} | |||
'''2)''' '''Study question''' - Effect of a Mediterranean diet on [[metabolic syndrome]] and its components. | '''2)''' '''Study question''' - Effect of a Mediterranean diet on [[metabolic syndrome]] and its components. | ||
Revision as of 15:46, 29 September 2011
|
Metabolic syndrome Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Metabolic syndrome dietary therapy On the Web |
|
American Roentgen Ray Society Images of Metabolic syndrome dietary therapy |
|
Risk calculators and risk factors for Metabolic syndrome dietary therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]
Overview
Dietary modifications are the first step in treatment of metabolic syndrome. It can be started in isolation or along with other medications. It helps by assisting in weight loss, thus increasing insulin sensitivity. Studies support that diet, exercise, and drug therapy may inhibit the progression of metabolic syndrome to diabetes mellitus.
Dietary modifications
Findings from various studies suggest that:
1) Westernized and higher fructose diets have increased risk for developing metabolic syndrome.
2) Mediterranean diet rich in fresh fruits, vegetables, whole grains, nuts, seeds, legumes, seafood, yogurt and olive oil lowers the risks for metabolic syndrome [1].
3) Some studies suggest that moderate red wine intake may protect against the development of metabolic syndrome [2]. However, further supportive evidences are required.
4) Interestingly, in a metanalysis chocolate was found to reduce the risks of coronary artery disease, cardiac deaths, diabetes, and stroke by approximately 30%. The possible explanation for this is the presence of polyphenols in chocolates that increases the concentration of nitric oxide (antioxidants) [3].
Trial supportive data
Meta-analysis on effect of Mediterranean diet on metabolic syndrome
1) Study design – Meta-analysis {50 original research studies (35 clinical trials, 2 prospective and 13 cross-sectional), with 534,906 participants, were included in the analysis}
2) Study question - Effect of a Mediterranean diet on metabolic syndrome and its components.
3) Study results -
- Mediterranean diet was associated with reduced risk of metabolic syndrome (log hazard ratio: -0.69, 95% confidence interval [CI]: -1.24 to -1.16)
- Also, statistically significant reduction in waist circumference, triglycerides, systolic and diastolic blood pressure and glucose was found. Additionally, an elevation of HDL cholesterol levels was demonstrated
See also
References
- ↑ Barnes DE (2011). "The mediterranean diet: good for the heart = good for the brain?". Ann Neurol. 69 (2): 226–8. doi:10.1002/ana.22376. PMID 21387364.
- ↑ Liu L, Wang Y, Lam KS, Xu A (2008). "Moderate wine consumption in the prevention of metabolic syndrome and its related medical complications". Endocr Metab Immune Disord Drug Targets. 8 (2): 89–98. PMID 18537695.
- ↑ Buitrago-Lopez A, Sanderson J, Johnson L, Warnakula S, Wood A, Di Angelantonio E; et al. (2011). "Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis". BMJ. 343: d4488. doi:10.1136/bmj.d4488. PMC 3163382. PMID 21875885.