Pulmonary embolism classification: Difference between revisions
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==Acute PE== | ==Acute PE== | ||
Pulmonary embolism is called acute, if the embolism is | Pulmonary embolism is called acute, if the embolism is | ||
*Situated centrally within the vascular lumen | *Based on '''time''' of appearance of Symptoms: | ||
*Occludes a vessel. | **Develop symptoms and signs '''immediately''' after obstruction of pulmonary vessels. | ||
*Based on characteristic of the embolus: | |||
**Situated centrally within the vascular lumen | |||
**Occludes a vessel. | |||
It also causes distention of the involved vessel. | It also causes distention of the involved vessel. | ||
Revision as of 15:48, 7 November 2011
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Pulmonary Embolism Microchapters |
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Diagnosis |
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Pulmonary Embolism Assessment of Probability of Subsequent VTE and Risk Scores |
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Treatment |
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Follow-Up |
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Special Scenario |
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Trials |
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Case Studies |
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Pulmonary embolism classification On the Web |
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Directions to Hospitals Treating Pulmonary embolism classification |
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Risk calculators and risk factors for Pulmonary embolism classification |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editors-in-Chief: Ujjwal Rastogi, MBBS [2]
Synonyms and keywords: PE
Overview
Pulmonary embolism is classified in two different ways based upon:
- Time of appearance of symptoms & Size of embolus : Acute vs Chronic
- Severity of the disease : Massive vs Submassive vs Low-risk
Acute PE
Pulmonary embolism is called acute, if the embolism is
- Based on time of appearance of Symptoms:
- Develop symptoms and signs immediately after obstruction of pulmonary vessels.
- Based on characteristic of the embolus:
- Situated centrally within the vascular lumen
- Occludes a vessel.
It also causes distention of the involved vessel.
Chronic PE
Chronic pulmonary embolism is a consequence of incomplete resolution of pulmonary embolism.
It has the following characteristic:
- Embolus is:
- Eccentric
- Contiguous with the vessel wall
- Embolus reducing the arterial diameter by ≥50%
- Evidence of recanalization within the thrombus
- Presence of an arterial web
Massive PE
In the past, "massive pulmonary embolism" has been defined on the basis of angiographic burden of emboli by using the Miller Index[1]. This is a retrospective diagnosis based upon the pulmonary angiogram that does not inform prospective decisions.
Recently American heart association[2] has proposed the following definition for Massive PE: Acute pulmonary embolism with sustained hypotension (systolic blood pressure <90 mm Hg for at least 15 minutes or requiring inotropic support, not due to a cause other than PE, such as arrhythmia, hypovolemia, sepsis, or left ventricular [LV] dysfunction), pulselessness, or persistent profound bradycardia (heart rate <40 bpm with signs or symptoms of shock).
Submassive PE
American heart association[2] has proposed the following definition for Submassive PE: "Acute PE without systemic hypotension (systolic blood pressure ≥90 mm Hg) but with either RV dysfunction or myocardial necrosis."
Low-risk PE
American heart association[2] has proposed the following definition for Low-risk PE: "Acute PE and the absence of the clinical markers of adverse prognosis that define massive or submassive PE."
References
- ↑ Miller GA, Sutton GC, Kerr IH, Gibson RV, Honey M (1971). "Comparison of streptokinase and heparin in treatment of isolated acute massive pulmonary embolism". Br Heart J. 33 (4): 616. PMID 5557502.
- ↑ 2.0 2.1 2.2 Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ; et al. (2011). "Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association". Circulation. 123 (16): 1788–830. doi:10.1161/CIR.0b013e318214914f. PMID 21422387.