Factor XIII deficiency: Difference between revisions
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Revision as of 20:16, 9 December 2011
For patient information click here
Factor XIII deficiency | |
ICD-10 | D68.2 |
---|---|
ICD-9 | 286.3 |
OMIM | 134570 134580 |
DiseasesDB | 31412 |
MeSH | D005177 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Factor XIII deficiency may occur very rarely, and can cause a severe bleeding tendency. Incidence is 1 in a million to 1 in 5 million people. Most are due to mutations in the A subunit. Administration of recombinant A subunit improves clot stability and may become a therapeutic option for patients with this condition[1].
See also
References
- ↑ Lovejoy A, Reynolds T, Visich J, Butine M, Young G, Belvedere M, Blain R, Pederson S, Ishak L, Nugent D (2006). "Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency". Blood. 108 (1): 57–62. PMID 16556896.