Pilocytic astrocytoma

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Overview

Pilocytic astrocytoma is a brain tumor that occurs predominantly in children and involves the midline, basal and posterior fossa structures. It is generally considered a benign tumor of childhood. It is often cystic and if solid, it tends to be well circumscribed. It is characteristically a contrast enhancing tumor by current imaging investigations (e.g. CT scan, MRI)

Microscopically, the tumor is composed of bipolar cells with long "hairlike" GFAP-positive processes. Rosenthal fibers, eosinophilic granular bodies and microcysts are often present.

It is classified as Grade 1 Astrocytoma.

External links

• Medical Image Database
• UC
• fightJPA - An Organization Dedicated to Funding Research into Juvenile Pilocytic Astrocytoma

Acknowledgements

The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.

Initial content for this page in some instances came from Wikipedia

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