Pulmonary embolism epidemiology and demographics: Difference between revisions

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{{Pulmonary embolism}}
{{Pulmonary embolism}}
{{CMG}}
{{CMG}}
'''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS]] [mailto:urastogi@perfuse.org]
'''Associate Editors-in-Chief:''' [[User:Ujjwal Rastogi|Ujjwal Rastogi, MBBS]] [mailto:urastogi@perfuse.org]


==Overview==
==Overview==
Each year in United States, there are between 300,000 and 600,000 cases of pulmonary embolism (PE). If un-treated almost 1/3 of patient die, usually from recurrent PE. However, with prompt diagnosis and treatment, the mortality rate is only ~ 2 – 8%. Unfortunately, 2/3 of all cases of PE are diagnosed only on autopsy. [http://stopdvt.org/Documents/AMA%20Fact%20Sheet%20Current%20Research.pdf] PE is the major contributing factor or a cause of death in 16% of the hospitalized patients.
Each year in United States, there are between 300,000-600,000 cases of pulmonary embolism (PE). If left untreated almost one-third of patients die, typically from recurrent PE. However, with prompt diagnosis and treatment, the mortality rate is only approximately 2–8%. Unfortunately, two-thirds of all cases of PE are diagnosed only on autopsy. <ref name="AHA2007"> American Heart Association. (2007). Venous Thromboembolism & Pulmonary Embolism - Statistical Fact Sheet: 2007 Update. Retreived from http://stopdvt.org/Documents/AMA%20Fact%20Sheet%20Current%20Research.pdf </ref> PE is the major contributing factor or a cause of death in 16% of the hospitalized patients.


==Epidemiology and Demographics==
==Epidemiology and Demographics==
''Horlander et al'' analyzed multiple-cause mortality files compiled by the National Center for Health Statistics from 1979 to 1998. They reported that out of 42932973 deaths that occurred, almost 600,000 patients (approximately 1.5 percent) had been diagnosed with PE, and it was the presumed cause of death in 200,00 patients.<ref name="pmid12885687">{{cite journal| author=Horlander KT, Mannino DM, Leeper KV| title=Pulmonary embolism mortality in the United States, 1979-1998: an analysis using multiple-cause mortality data. | journal=Arch Intern Med | year= 2003 |volume= 163 | issue= 14 | pages= 1711-7 | pmid=12885687 | doi=10.1001/archinte.163.14.1711 | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12885687  }}</ref>
''Horlander et al'' analyzed multiple-cause mortality files compiled by the National Center for Health Statistics from 1979 to 1998. They reported that out of 42,932,973 deaths that occurred, almost 600,000 patients (approximately 1.5 percent) had been diagnosed with PE. They also theorized it was the presumed cause of death in 200,000 patients.<ref name="pmid12885687">{{cite journal| author=Horlander KT, Mannino DM, Leeper KV| title=Pulmonary embolism mortality in the United States, 1979-1998: an analysis using multiple-cause mortality data. | journal=Arch Intern Med | year= 2003 |volume= 163 | issue= 14 | pages= 1711-7 | pmid=12885687 | doi=10.1001/archinte.163.14.1711 | pmc= |url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12885687  }}</ref>


The incidence [[Pulmonary embolism classification scheme#Massive PE|massive]], [[Pulmonary embolism classification scheme#Submassive PE|submassive]]  and  [[Pulmonary embolism classification scheme#Low-risk PE|low-risk]]  are 5%, 40% and 55% respectively.  
The incidence rate of [[Pulmonary embolism classification scheme#Massive PE|massive]], [[Pulmonary embolism classification scheme#Submassive PE|submassive]]  and  [[Pulmonary embolism classification scheme#Low-risk PE|low-risk]]  are 5%, 40% and 55% respectively.  


Only 10-20% of VTE is clinically recognized, as depicted by the figure below.
Only 10-20% of VTE is clinically recognized, as depicted by the figure below.

Revision as of 17:00, 16 December 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editors-in-Chief: Ujjwal Rastogi, MBBS [2]

Overview

Each year in United States, there are between 300,000-600,000 cases of pulmonary embolism (PE). If left untreated almost one-third of patients die, typically from recurrent PE. However, with prompt diagnosis and treatment, the mortality rate is only approximately 2–8%. Unfortunately, two-thirds of all cases of PE are diagnosed only on autopsy. [1] PE is the major contributing factor or a cause of death in 16% of the hospitalized patients.

Epidemiology and Demographics

Horlander et al analyzed multiple-cause mortality files compiled by the National Center for Health Statistics from 1979 to 1998. They reported that out of 42,932,973 deaths that occurred, almost 600,000 patients (approximately 1.5 percent) had been diagnosed with PE. They also theorized it was the presumed cause of death in 200,000 patients.[2]

The incidence rate of massive, submassive and low-risk are 5%, 40% and 55% respectively.

Only 10-20% of VTE is clinically recognized, as depicted by the figure below.

References

  1. American Heart Association. (2007). Venous Thromboembolism & Pulmonary Embolism - Statistical Fact Sheet: 2007 Update. Retreived from http://stopdvt.org/Documents/AMA%20Fact%20Sheet%20Current%20Research.pdf
  2. Horlander KT, Mannino DM, Leeper KV (2003). "Pulmonary embolism mortality in the United States, 1979-1998: an analysis using multiple-cause mortality data". Arch Intern Med. 163 (14): 1711–7. doi:10.1001/archinte.163.14.1711. PMID 12885687.

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