Monoarticular arthritis

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Evidence Based Medicine
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Clinical Trials
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Differential Diagnosis

Common causes

• Avascular necrosis of bone
• Crystals

• Monosodium urate
• Calcium pyrophosphate dihydrate
• Apatite
• Calcium oxalate

• Hemarthrosis
• Infectious arthritis

• Bacteria
• Fungi

Still’s disease Mycobacteria Synovioma Viruses Synovial metastasis Lyme disease Vasculitic syndromes

Internal derangement

Osteoarthritis

Osteomyelitis

Overuse

Trauma

Less Common Causes

• Bone malignancies
• Bowel-disease–associated arthritis
• Hemoglobinopathies
• Juvenile rheumatoid arthritis
• Loose body
• Psoriatic arthritis
• Rheumatoid arthritis
• Reactive arthritis
• Sarcoidosis

Rare Causes

• Amyloidosis
• Behçet’s syndrome
• Familial Mediterranean Fever
• Foreign-body synovitis
• Hypertrophic pulmonary
• Osteoarthropathy
• Intermittent hydrarthrosis
• Pigmented villonodular synovitis
• Relapsing polychondritis