Alprazolam contraindications: Difference between revisions

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==Contraindications==
==List of contraindications==
Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma.
<font size="4">[[Alprazolam contraindications#Benzodiazepine sensitivity|Benzodiazepine sensitivity]]</font>
 
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Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A).
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<font size="4">[[Alprazolam contraindications#Narrow angle glaucoma|Narrow angle glaucoma]]</font>
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<font size="4">[[Alprazolam contraindications#Ketoconazole & itraconazole|Ketoconazole & itraconazole]]</font>
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===Benzodiazepine sensitivity===
Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. ''[[Alprazolam contraindications#List of contraindications|Return to top]]''
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===Narrow angle glaucoma===
Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma. ''[[Alprazolam contraindications#List of contraindications|Return to top]]''
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===Ketoconazole & itraconazole===
Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A). ''[[Alprazolam contraindications#List of contraindications|Return to top]]''
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{{FDA}}
{{FDA}}

Revision as of 20:39, 19 December 2011

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

List of contraindications

Benzodiazepine sensitivity

Narrow angle glaucoma

Ketoconazole & itraconazole



Benzodiazepine sensitivity

Alprazolam is contraindicated in patients with known sensitivity to this drug or other benzodiazepines. Return to top

Narrow angle glaucoma

Alprazolam may be used in patients with open angle glaucoma who are receiving appropriate therapy, but is contraindicated in patients with acute narrow angle glaucoma. Return to top

Ketoconazole & itraconazole

Alprazolam is contraindicated with ketoconazole and itraconazole, since these medications significantly impair the oxidative metabolism mediated by cytochrome P450 3A (CYP3A). Return to top



Adapted from the FDA Package Insert.