Thymoma overview: Difference between revisions
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==Overview== | ==Overview== | ||
In [[medicine]] ([[oncology]]), '''thymoma''' is a [[tumor]] originating from the [[thymus]]. It consists of any type of thymic [[epithelial cell]] as well as [[lymphocyte]]s that are usually abundant and probably not [[neoplastic]]. Thymoma usually is [[benign]], and frequently encapsulated; when occasionally [[malignant]], then it is [[invasive]]: [[metastasis]] is extremely rare. Malignant [[lymphomas]] that involve the thymus, e.g., [[lymphosarcoma]], [[Hodgkin's disease]] (termed "granulomatous thymoma" in the past), should not be regarded as thymoma. Thymoma is a [[rare disease]], best known for its enigmatic association with the neuromuscular disorder [[myasthenia gravis]].<ref name=Thomas1999>{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=J. Clin. Oncol. |volume=17 |issue=7 |pages=2280–9 |year=1999 |pmid=10561285 |doi=}}</ref> | In [[medicine]] ([[oncology]]), '''thymoma''' is a [[tumor]] originating from the [[thymus]]. It consists of any type of thymic [[epithelial cell]] as well as [[lymphocyte]]s that are usually abundant and probably not [[neoplastic]]. Thymoma usually is [[benign]], and frequently encapsulated; when occasionally [[malignant]], then it is [[invasive]]: [[metastasis]] is extremely rare. Malignant [[lymphomas]] that involve the thymus, e.g., [[lymphosarcoma]], [[Hodgkin's disease]] (termed "granulomatous thymoma" in the past), should not be regarded as thymoma. Thymoma is a [[rare disease]], best known for its enigmatic association with the neuromuscular disorder [[myasthenia gravis]].<ref name=Thomas1999>{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=J. Clin. Oncol. |volume=17 |issue=7 |pages=2280–9 |year=1999 |pmid=10561285 |doi=}}</ref> | ||
Thymomas associated with autoimmune disorders usually are benign. Malignant thymomas can [[metastasis|metastasize]], generally to [[pleura]], [[kidney]], [[bone]], [[liver]] or [[brain]].<ref name="pmid10561285">{{cite journal |author=Thomas CR, Wright CD, Loehrer PJ |title=Thymoma: state of the art |journal=[[Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology]] |volume=17 |issue=7 |pages=2280–9 |year=1999 |month=July |pmid=10561285 |doi= |url=http://www.jco.org/cgi/pmidlookup?view=long&pmid=10561285 |accessdate=2012-01-18}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 18:59, 18 January 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
In medicine (oncology), thymoma is a tumor originating from the thymus. It consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant and probably not neoplastic. Thymoma usually is benign, and frequently encapsulated; when occasionally malignant, then it is invasive: metastasis is extremely rare. Malignant lymphomas that involve the thymus, e.g., lymphosarcoma, Hodgkin's disease (termed "granulomatous thymoma" in the past), should not be regarded as thymoma. Thymoma is a rare disease, best known for its enigmatic association with the neuromuscular disorder myasthenia gravis.[1]
Thymomas associated with autoimmune disorders usually are benign. Malignant thymomas can metastasize, generally to pleura, kidney, bone, liver or brain.[2]
References
- ↑ Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". J. Clin. Oncol. 17 (7): 2280–9. PMID 10561285.
- ↑ Thomas CR, Wright CD, Loehrer PJ (1999). "Thymoma: state of the art". Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17 (7): 2280–9. PMID 10561285. Retrieved 2012-01-18. Unknown parameter
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