Chronic myelogenous leukemia laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
Patients are often [[asymptomatic]] at diagnosis, presenting incidentally with an elevated [[white blood cell]] count on a routine laboratory test. In this setting, CML must be distinguished from a [[leukemoid reaction]], which can have a similar appearance on a [[blood film|blood smear]]. | Patients are often [[asymptomatic]] at diagnosis, presenting incidentally with an elevated [[white blood cell]] count on a routine laboratory test. In this setting, CML must be distinguished from a [[leukemoid reaction]], which can have a similar appearance on a [[blood film|blood smear]]. | ||
==Laboratory tests== | |||
CML is often suspected on the basis on the [[complete blood count]], which shows increased [[granulocyte]]s of all types, typically including immature myeloid cells. [[Basophil]]s and [[eosinophil]]s are almost universally increased; this feature may help differentiate CML from a [[leukemoid reaction]]. | |||
[[Image:CDR554337-274.jpg|center|thumb|450px|Bone marrow aspiration and biopsy. After a small area of skin is numbed, a Jamshidi needle (a long, hollow needle) is inserted into the patient’s hip bone. Samples of blood, bone, and bone marrow are removed for examination under a microscope. [http://www.cancer.gov/cancertopics/pdq/treatment/CML/patient/ Source]]] | |||
==References== | ==References== | ||
Revision as of 16:04, 20 January 2012
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Chronic myelogenous leukemia Microchapters |
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Differentiating Chronic myelogenous leukemia from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Chronic myelogenous leukemia laboratory tests On the Web |
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American Roentgen Ray Society Images of Chronic myelogenous leukemia laboratory tests |
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Directions to Hospitals Treating Chronic myelogenous leukemia |
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Risk calculators and risk factors for Chronic myelogenous leukemia laboratory tests |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Patients are often asymptomatic at diagnosis, presenting incidentally with an elevated white blood cell count on a routine laboratory test. In this setting, CML must be distinguished from a leukemoid reaction, which can have a similar appearance on a blood smear.
Laboratory tests
CML is often suspected on the basis on the complete blood count, which shows increased granulocytes of all types, typically including immature myeloid cells. Basophils and eosinophils are almost universally increased; this feature may help differentiate CML from a leukemoid reaction.
