Paraganglioma: Difference between revisions
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==[[Paraganglioma history and symptoms|History & Symptoms]]== | ==[[Paraganglioma history and symptoms|History & Symptoms]]== | ||
==[[ | '''For patient information click [[Paraganglioma (patient information)|here]]''' | ||
{{Paraganglioma}} | |||
{{CMG}} | |||
==Overview== | |||
A '''paraganglioma''' is a rare [[neoplasm]] that can be found in the abdomen, thorax, and in the head and neck region. They are usually considered [[benign]] and complete surgical removal results in cure. However, in about 3% of cases they are [[malignant]] and have the ability to [[metastasis|metastasize]]. Paragangliomas are still sometimes called '''glomus tumors''' (not to be confused with [[glomus tumor]]s of the skin) and '''chemodectomas''', but paraganglioma is the currently accepted and preferred term. | |||
Paragangliomas arise from the [[glomus cell]]s, which are special [[chemoreceptor]]s located along blood vessels that have a role in regulating blood pressure and blood flow. The main concentration of glomus cells are found are in the [[carotid body]], located in the upper neck at the branching of the [[carotid artery|common carotid artery]], and the [[aortic body|aortic bodies]], located near the [[aorta|aortic arch]]. The glomus cells are a part of the paraganglion system composed of the extra-adrenal [[paraganglia]] of the [[autonomic nervous system]], derived from the embryonic [[neural crest]]. Thus, paragangliomas are a type of [[neuroendocrine tumor]], and are closely related to [[pheochromocytoma]]s. Although all paragangliomas contain neurosecretory granules, only about 1-3% have clinical evidence of oversecretion. | |||
==Surgery== | |||
The main treatment modalities are surgery, [[embolization]] and [[radiotherapy]]. | The main treatment modalities are surgery, [[embolization]] and [[radiotherapy]]. | ||
==References== | |||
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{{Epithelial neoplasms}} | |||
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[[Category:Disease]] | |||
[[Category:Types of cancer]] | |||
[[Category:Oncology]] | |||
[[Category:Mature chapter]] | |||
==References== | ==References== | ||
Revision as of 19:08, 20 January 2012
For patient information click here
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Paraganglioma Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Paraganglioma On the Web |
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American Roentgen Ray Society Images of Paraganglioma |
| Paraganglioma | |
| ICD-O: | 8680-8700 |
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| DiseasesDB | 33480 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes of Paraganglioma
Pathophysiology
History & Symptoms
For patient information click here
|
Paraganglioma Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Paraganglioma On the Web |
|
American Roentgen Ray Society Images of Paraganglioma |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]
Overview
A paraganglioma is a rare neoplasm that can be found in the abdomen, thorax, and in the head and neck region. They are usually considered benign and complete surgical removal results in cure. However, in about 3% of cases they are malignant and have the ability to metastasize. Paragangliomas are still sometimes called glomus tumors (not to be confused with glomus tumors of the skin) and chemodectomas, but paraganglioma is the currently accepted and preferred term.
Paragangliomas arise from the glomus cells, which are special chemoreceptors located along blood vessels that have a role in regulating blood pressure and blood flow. The main concentration of glomus cells are found are in the carotid body, located in the upper neck at the branching of the common carotid artery, and the aortic bodies, located near the aortic arch. The glomus cells are a part of the paraganglion system composed of the extra-adrenal paraganglia of the autonomic nervous system, derived from the embryonic neural crest. Thus, paragangliomas are a type of neuroendocrine tumor, and are closely related to pheochromocytomas. Although all paragangliomas contain neurosecretory granules, only about 1-3% have clinical evidence of oversecretion.
Surgery
The main treatment modalities are surgery, embolization and radiotherapy.
References
de:Paragangliom nl:Paraganglioom sk:Paraganglióm