Zollinger-Ellison syndrome: Difference between revisions

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==Treatment==
==Treatment==
[[Zollinger-Ellison syndrome medical therapy|Medical therapy]] | [[Zollinger-Ellison syndrome surgery|Surgical options]] | [[Zollinger-Ellison syndrome primary prevention|Primary prevention]]  | [[Zollinger-Ellison syndrome secondary prevention|Secondary prevention]] | [[Zollinger-Ellison syndrome cost-effectiveness of therapy|Financial costs]] | [[Zollinger-Ellison syndrome future or investigational therapies|Future therapies]]
[[Zollinger-Ellison syndrome medical therapy|Medical therapy]] | [[Zollinger-Ellison syndrome surgery|Surgical options]] | [[Zollinger-Ellison syndrome primary prevention|Primary prevention]]  | [[Zollinger-Ellison syndrome secondary prevention|Secondary prevention]] | [[Zollinger-Ellison syndrome cost-effectiveness of therapy|Financial costs]] | [[Zollinger-Ellison syndrome future or investigational therapies|Future therapies]]
==Therapy==
[[Proton pump inhibitor]]s (such as [[omeprazole]] and [[lansoprazole]]) and histamine [[H2-receptor antagonist]]s (such as [[famotidine]] and [[ranitidine]]) are used to slow down acid secretion. If possible the tumours should be surgically removed, or treated with [[chemotherapy]].
[[Octreotide]] can be used to slow down acid secretion.


==History==
==History==

Revision as of 19:15, 20 January 2012

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Zollinger-Ellison syndrome
Endoscopy image of multiple small ulcers in the distal duodenum in a patient with Zollinger-Ellison syndrome
ICD-10 E16.4
ICD-9 251.5
MedlinePlus 000325
eMedicine med/2437  ped/2472
MeSH D015043

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History

The disease entity was first described in 1955 by its namesakes: Zollinger RM, Ellison EH. Primary peptic ulcerations of the jejunum associated with islet cell tumors of the pancreas. Ann Surg 1955;142:709-23. PMID 13259432.

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