Polycythemia vera epidemiology and demographics: Difference between revisions
Created page with "{{CMG}} {{Polycythemia vera}} ==Overview== '''Primary polycythemia''', often called '''polycythemia vera''' (PCV), polycythemia rubra vera (PRV), or erythremia, occur..." |
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==Overview== | ==Overview== | ||
'''Primary [[polycythemia]]''', often called '''[[polycythemia vera]]''' (PCV), polycythemia rubra vera (PRV), or erythremia, occurs when excess red blood cells are produced as a result of an abnormality of the [[bone marrow]]. Often, excess [[white blood cell]]s and [[platelet]]s are also produced. Polycythemia vera is classified as a [[myeloproliferative disease]]. | '''Primary [[polycythemia]]''', often called '''[[polycythemia vera]]''' (PCV), polycythemia rubra vera (PRV), or erythremia, occurs when excess red blood cells are produced as a result of an abnormality of the [[bone marrow]]. Often, excess [[white blood cell]]s and [[platelet]]s are also produced. Polycythemia vera is classified as a [[myeloproliferative disease]]. | ||
==Epidemiology and demographics== | |||
'''Polycythemia vera''' occurs in all age groups (including children),<ref>{{cite journal | author = Passamonti F, Malabarba L, Orlandi E, Baratè C, Canevari A, Brusamolino E, Bonfichi M, Arcaini L, Caberlon S, Pascutto C, Lazzarino M | title = Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia. | journal = Haematologica | volume = 88 | issue = 1 | pages = 13-8 | year = 2003 | id = PMID 12551821}}</ref> although the incidence increases with age. One study found the median age at diagnosis to be 60 years,<ref name="pvsg">Berlin, NI. (1975). "Diagnosis and classification of polycythemias". ''Semin Hematol'' '''12''': 339.</ref> while a study in Olmsted County, Minnesota found that the highest incidence was in people aged 70–79 years.<ref name="olmsted">{{cite journal | author = Anía B, Suman V, Sobell J, Codd M, Silverstein M, Melton L | title = Trends in the incidence of polycythemia vera among Olmsted County, Minnesota residents, 1935-1989. | journal = Am J Hematol | volume = 47 | issue = 2 | pages = 89-93 | year = 1994 | id = PMID 8092146}}</ref> The overall incidence in the Minnesota population was 1.9 per 100,000 person-years, and the disease was more common in men than women.<ref name="olmsted"/> | |||
==References== | ==References== | ||
Revision as of 16:18, 21 January 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Primary polycythemia, often called polycythemia vera (PCV), polycythemia rubra vera (PRV), or erythremia, occurs when excess red blood cells are produced as a result of an abnormality of the bone marrow. Often, excess white blood cells and platelets are also produced. Polycythemia vera is classified as a myeloproliferative disease.
Epidemiology and demographics
Polycythemia vera occurs in all age groups (including children),[1] although the incidence increases with age. One study found the median age at diagnosis to be 60 years,[2] while a study in Olmsted County, Minnesota found that the highest incidence was in people aged 70–79 years.[3] The overall incidence in the Minnesota population was 1.9 per 100,000 person-years, and the disease was more common in men than women.[3]
References
- ↑ Passamonti F, Malabarba L, Orlandi E, Baratè C, Canevari A, Brusamolino E, Bonfichi M, Arcaini L, Caberlon S, Pascutto C, Lazzarino M (2003). "Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia". Haematologica. 88 (1): 13–8. PMID 12551821.
- ↑ Berlin, NI. (1975). "Diagnosis and classification of polycythemias". Semin Hematol 12: 339.
- ↑ 3.0 3.1 Anía B, Suman V, Sobell J, Codd M, Silverstein M, Melton L (1994). "Trends in the incidence of polycythemia vera among Olmsted County, Minnesota residents, 1935-1989". Am J Hematol. 47 (2): 89–93. PMID 8092146.