Myelofibrosis laboratory tests: Difference between revisions
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* Raised levels of [[lactate dehydrogenase]] | * Raised levels of [[lactate dehydrogenase]] | ||
* Raised neutrophil alkaline phosphatase score | * Raised neutrophil alkaline phosphatase score | ||
====TB testing==== | |||
The patient with the myelofibrosis should be tested for [[Tuberculosis]] even if the patient doesn't manifest the symptoms of TB. There is strong evidence of myelofibrois improvement with the antituberculous treatment. | |||
==References== | ==References== | ||
Revision as of 18:06, 22 January 2012
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Myelofibrosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Myelofibrosis laboratory tests On the Web |
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American Roentgen Ray Society Images of Myelofibrosis laboratory tests |
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Risk calculators and risk factors for Myelofibrosis laboratory tests |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Tests
Diagnosis is based upon:
- Normochromic normocytic anaemia
- Red cell poikilocytosis on blood film (tear-drop shaped RBCs)
- JAK 2 mutation on Val 617 Phe locus in 50%
- Raised levels of lactate dehydrogenase
- Raised neutrophil alkaline phosphatase score
TB testing
The patient with the myelofibrosis should be tested for Tuberculosis even if the patient doesn't manifest the symptoms of TB. There is strong evidence of myelofibrois improvement with the antituberculous treatment.