Langerhans cell histiocytosis history and symptoms: Difference between revisions
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{{Langerhans cell histiocytosis}} | {{Langerhans cell histiocytosis}} | ||
{{CMG}} | {{CMG}} | ||
==Overview== | |||
Features can be non-specific from generalized inflammatory response e.g fever, lethargy, weight loss or can be due to specific organ involvement. | |||
==History and Symptoms== | ==History and Symptoms== | ||
*Histiocytosis X often affects the whole body. A disease that affects the whole body is called a systemic disorder. | |||
*Symptoms can vary between children and adults, although there can be some overlap. Tumors in weight-bearing bones, such as the legs or spine, may cause the bones to fracture without apparent reason. | |||
*Symptoms in children may include: | |||
:*[[Abdominal pain]] | |||
:*[[Bone pain]] (possibly) | |||
:*[[Delayed puberty]] | |||
:*[[Dizziness]] | |||
:*Ear drainage that continues long-term | |||
:*Eyes that appear to stick out (protrude) more and more | |||
:*Irritability | |||
:*[[Failure to thrive]] | |||
:*[[Fever]] | |||
:*Frequent urination | |||
:*[[Headache]] | |||
:*[[Jaundice]] | |||
:*Limping | |||
:*Mental deterioration | |||
:*[[Rash]] ([[petechiae]] or [[purpura]]) | |||
:*[[Seborrheic dermatitis]] of the scalp | |||
:*[[Seizures]] | |||
:*[[Short stature]] | |||
:*Swollen lymph glands | |||
:*Thirst | |||
:*[[Vomiting]] | |||
:*[[Weight loss]] | |||
''Note: Children over 5 years old often have only bone involvement.'' | |||
*Symptoms in adults may include: | |||
:*[[Bone pain]] | |||
:*[[Chest pain]] | |||
:*[[Cough]] | |||
:*[[Fever]] | |||
:*General discomfort, uneasiness, or ill feeling (malaise) | |||
:*Increased amount of urine | |||
:*[[Rash]] | |||
:*[[Shortness of breath]] | |||
:*Thirst and increased drinking of fluids | |||
:*[[Weight loss]] | |||
==References== | ==References== | ||
Revision as of 03:31, 30 January 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Features can be non-specific from generalized inflammatory response e.g fever, lethargy, weight loss or can be due to specific organ involvement.
History and Symptoms
- Histiocytosis X often affects the whole body. A disease that affects the whole body is called a systemic disorder.
- Symptoms can vary between children and adults, although there can be some overlap. Tumors in weight-bearing bones, such as the legs or spine, may cause the bones to fracture without apparent reason.
- Symptoms in children may include:
- Abdominal pain
- Bone pain (possibly)
- Delayed puberty
- Dizziness
- Ear drainage that continues long-term
- Eyes that appear to stick out (protrude) more and more
- Irritability
- Failure to thrive
- Fever
- Frequent urination
- Headache
- Jaundice
- Limping
- Mental deterioration
- Rash (petechiae or purpura)
- Seborrheic dermatitis of the scalp
- Seizures
- Short stature
- Swollen lymph glands
- Thirst
- Vomiting
- Weight loss
Note: Children over 5 years old often have only bone involvement.
- Symptoms in adults may include:
- Bone pain
- Chest pain
- Cough
- Fever
- General discomfort, uneasiness, or ill feeling (malaise)
- Increased amount of urine
- Rash
- Shortness of breath
- Thirst and increased drinking of fluids
- Weight loss