Primary sclerosing cholangitis: Difference between revisions

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Revision as of 22:13, 7 February 2012

For patient information click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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 ==Therapy==
-Standard treatment includes [[ursodiol]], a bile acid naturally produced by the liver, which has been shown to lower elevated liver enzyme numbers in people with PSC, but has not yet been proven effective at prolonging the life of the liver.  Treatment also includes medication to relieve itching ([[antipruritic]]s) and bile acid sequesterants (cholestyramine), [[antibiotic]]s to treat infections, and [[vitamin]] supplements, as people with PSC are often deficient in [[vitamin A]], [[vitamin D]], and [[vitamin K]].
-In some cases, ERCP, which may involve stenting of the common bile duct, may be necessary in order to open major blockages (dominant strictures).
-[[Liver transplantation]] (including live transplants whereby a portion of a living donor is given to the recipient) is an option if the liver begins to fail.
 == See also ==