Measles pathophysiology: Difference between revisions
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==Overview== | ==Overview== | ||
==Virology== | |||
Measles virus (MV) is an enveloped, nonsegmented negative-stranded RNA virus of the [[Paramyxoviridae]] family. | |||
==Transmission== | |||
The measles is a highly contagious airborne pathogen which spreads primarily via the respiratory system. The virus is transmitted in respiratory secretions, and can be passed from person to person via aerosol droplets containing virus particles, such as those produced by a coughing patient. Once transmission occurs, the virus infects the epithelial cells of its new host, and may also replicate in the urinary tract, lymphatic system, conjunctivae, blood vessels, and central nervous system.<ref name="principlesofvirology">{{cite book | author = Flint SJ, Enquist LW, Racaniello VR, and AM Skalka | title = Principles of Virology, 2nd edition: Molecular Biology, Pathogenesis, and Control of Animal Viruses | 2004}}</ref> | |||
Humans are the only known natural hosts of measles, although the virus can infect some non-human primate species. | |||
==References== | ==References== |
Revision as of 20:53, 8 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Virology
Measles virus (MV) is an enveloped, nonsegmented negative-stranded RNA virus of the Paramyxoviridae family.
Transmission
The measles is a highly contagious airborne pathogen which spreads primarily via the respiratory system. The virus is transmitted in respiratory secretions, and can be passed from person to person via aerosol droplets containing virus particles, such as those produced by a coughing patient. Once transmission occurs, the virus infects the epithelial cells of its new host, and may also replicate in the urinary tract, lymphatic system, conjunctivae, blood vessels, and central nervous system.[1]
Humans are the only known natural hosts of measles, although the virus can infect some non-human primate species.