Meningococcemia natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
|||
| Line 6: | Line 6: | ||
==Natural History== | ==Natural History== | ||
* Before antibiotics the case fatality rate was over 50%, particularly dangerous in infants and elderly (84% and 72% respectively). Now it is often as low as 8% in major medical centers. | * Before antibiotics the case fatality rate was over 50%, particularly dangerous in infants and elderly (84% and 72% respectively). Now it is often as low as 8% in major medical centers. | ||
==Risk Stratification and Prognosis== | |||
* Current vaccines have polysaccharides of groups A, C, Y, and W-135. No vaccine available presently for group B disease since the polysaccharide is not sufficiently immunogenic to produce a reliable antibody response in humans to be effective. | |||
* Rates of meningococcus in US college students as a whole 0.7 per 100,000. | |||
* Rates of meningococcus in US persons aged 18-23 not in college 1.5 per 100,000. | |||
* Rates of freshmen living in dormitories 4.6 per 100,000. | |||
* Rates for college students in UK 13.2 per 100,000 versus those not in college of 5.5 per 100,000. | |||
==References== | ==References== | ||
Revision as of 21:20, 8 February 2012
|
Meningococcemia Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Meningococcemia natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Meningococcemia natural history, complications and prognosis |
|
FDA on Meningococcemia natural history, complications and prognosis |
|
CDC on Meningococcemia natural history, complications and prognosis |
|
Meningococcemia natural history, complications and prognosis in the news |
|
Blogs on Meningococcemia natural history, complications and prognosis |
|
Risk calculators and risk factors for Meningococcemia natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Natural History
- Before antibiotics the case fatality rate was over 50%, particularly dangerous in infants and elderly (84% and 72% respectively). Now it is often as low as 8% in major medical centers.
Risk Stratification and Prognosis
- Current vaccines have polysaccharides of groups A, C, Y, and W-135. No vaccine available presently for group B disease since the polysaccharide is not sufficiently immunogenic to produce a reliable antibody response in humans to be effective.
- Rates of meningococcus in US college students as a whole 0.7 per 100,000.
- Rates of meningococcus in US persons aged 18-23 not in college 1.5 per 100,000.
- Rates of freshmen living in dormitories 4.6 per 100,000.
- Rates for college students in UK 13.2 per 100,000 versus those not in college of 5.5 per 100,000.