Syphilis pathophysiology

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Casusative organism: Treponema Pallidum

• Small spirochete
• Transmission: requires direct contact with infectious lesion
• Common modes of transmission: vertical transmission, via blood transfusion, via sexual contact
• Light microscope: Invisible
• Dark field microscope: Distinctive undulating movement seen

Histopathological Findings

Brain: Gumma of syphilis

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Brain: Paresis (syphilis)

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References

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