Mononucleosis natural history: Difference between revisions
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==Overview== | ==Overview== | ||
== | ==Prognosis== | ||
Fatalities from mononucleosis are extremely rare in developed nations. Potential mortal complications include splenic rupture, bacterial [[superinfection]]s, [[hepatic failure]] and the development of [[Myocarditis|viral myocarditis]]. | |||
==Complications== | |||
=====Hematological===== | |||
*[[Autoimmune hemolytic anemia]] | |||
*[[Thrombocytopenia]] | |||
*[[Granulocytopenia]] | |||
*[[Splenic rupture]] | |||
=====Neurological===== | |||
*Cranial nerve palsies (Bell’s palsy) | |||
*[[Encephalitis]] | |||
=====Hepatology===== | |||
*[[Hepatitis]] | |||
=====Cardiology===== | |||
*[[Pericarditis]] | |||
*[[Myocarditis]] | |||
=====Respiratory===== | |||
*Airway obstruction ([[adenopathy]]) | |||
=====Non-fatal compliactions===== | |||
Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection: | Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection: | ||
*CNS: [[Meningitis]], [[encephalitis]], [[hemiplegia]] and transverse [[myelitis]]. EBV infection has also been proposed as a risk factor for the development of [[multiple sclerosis]] (MS)<ref>{{cite journal |author=Ascherio A, Munger KL |title=Environmental risk factors for multiple sclerosis. Part I: the role of infection |journal=Ann. Neurol. |volume=61 |issue=4 |pages=288–99 |year=2007 |pmid=17444504 |doi=10.1002/ana.21117}}</ref>, but this has not been affirmed. | *CNS: [[Meningitis]], [[encephalitis]], [[hemiplegia]] and transverse [[myelitis]]. EBV infection has also been proposed as a risk factor for the development of [[multiple sclerosis]] (MS)<ref>{{cite journal |author=Ascherio A, Munger KL |title=Environmental risk factors for multiple sclerosis. Part I: the role of infection |journal=Ann. Neurol. |volume=61 |issue=4 |pages=288–99 |year=2007 |pmid=17444504 |doi=10.1002/ana.21117}}</ref>, but this has not been affirmed. | ||
Revision as of 16:46, 21 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Prognosis
Fatalities from mononucleosis are extremely rare in developed nations. Potential mortal complications include splenic rupture, bacterial superinfections, hepatic failure and the development of viral myocarditis.
Complications
Hematological
Neurological
- Cranial nerve palsies (Bell’s palsy)
- Encephalitis
Hepatology
Cardiology
Respiratory
- Airway obstruction (adenopathy)
Non-fatal compliactions
Uncommon, nonfatal complications exist, including various forms of CNS and hematological affection:
- CNS: Meningitis, encephalitis, hemiplegia and transverse myelitis. EBV infection has also been proposed as a risk factor for the development of multiple sclerosis (MS)[1], but this has not been affirmed.
- Hematologic: EBV can cause autoimmune hemolytic anemia (direct Coombs test is positive) and various cytopenias.
References
- ↑ Ascherio A, Munger KL (2007). "Environmental risk factors for multiple sclerosis. Part I: the role of infection". Ann. Neurol. 61 (4): 288–99. doi:10.1002/ana.21117. PMID 17444504.