Mononucleosis epidemiology and demographics: Difference between revisions
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==Overview== | ==Overview== | ||
[[EBV|Epstein | [[EBV|Epstein barr virus]] occurs worldwide, and most people become infected with [[EBV]] sometime during their lives. True outbreaks of infectious mononucleosis are extremely rare. A substantial number of '''''pseudo-outbreaks''''' have been linked to laboratory error[http://www.cdc.gov/mmwr/preview/mmwrhtml/00014974.htm]. Additionally, the dormant feature combined with long (4 to 6 week) incubation period of the disease, makes '''''epidemiological control of the disease impractical'''''. | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== |
Revision as of 21:39, 28 February 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]
Overview
Epstein barr virus occurs worldwide, and most people become infected with EBV sometime during their lives. True outbreaks of infectious mononucleosis are extremely rare. A substantial number of pseudo-outbreaks have been linked to laboratory error[3]. Additionally, the dormant feature combined with long (4 to 6 week) incubation period of the disease, makes epidemiological control of the disease impractical.
Epidemiology and Demographics
Age
- In the United States, as many as 95% of adults between 35 and 40 years of age have been infected with approximately 50% of the population seroconverts during early childhood.
- Infants become susceptible to EBV as soon as maternal antibody protection which is present at birth starts to disappears.
- Children if infected with EBV usually remain asymptomatic and hence are indistinguishable from the other mild, brief illnesses of childhood. However, when the infection occurs during adolescence or young adulthood, it causes acute infectious mononucleosis 35% to 50% of the time.