Aortic sclerosis overview: Difference between revisions
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* Commissural areas are spared | * Commissural areas are spared | ||
* Leaflet mobility is normal | * Leaflet mobility is normal | ||
* Valvular hemodynamic parameters are normal | * Valvular hemodynamic parameters are normal with a jet velocity of less than 2.5 m per sec across the valve | ||
==References== | ==References== | ||
Revision as of 21:21, 10 April 2012
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Aortic sclerosisMicrochapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Aortic sclerosis overview On the Web |
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American Roentgen Ray Society Images of Aortic sclerosis overview |
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Risk calculators and risk factors for Aortic sclerosis overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]
Overview
Aortic sclerosis commonly affects elderly population. Microscopic changes reveal lipoprotein accumulation, cellular infiltration and extracellular matrix formation that cause progressive thickening of the aortic valve.[1]
Epidemiology
Majority of the patients with aortic sclerosis are aged beyond 65 years and are associated with a significant increase in the risk of cardiovascular death, myocardial infarction even in the absence of hemodynamically significant left ventricular outflow tract obstruction.[2][3][4]
Diagnosis
History and Symptoms
- Mostly asymptomatic
- Aortic sclerosis is an incidental echocardiographic finding
Physical Examination
Echocardiography
- Focal areas of valve thickening as opposed to diffuse thickening observed in normal aging
- Commissural areas are spared
- Leaflet mobility is normal
- Valvular hemodynamic parameters are normal with a jet velocity of less than 2.5 m per sec across the valve
References
- ↑ Freeman RV, Otto CM (2005). "Spectrum of calcific aortic valve disease: pathogenesis, disease progression, and treatment strategies". Circulation. 111 (24): 3316–26. doi:10.1161/CIRCULATIONAHA.104.486738. PMID 15967862. Retrieved 2012-04-10. Unknown parameter
|month=ignored (help) - ↑ Lindroos M, Kupari M, Heikkilä J, Tilvis R (1993). "Prevalence of aortic valve abnormalities in the elderly: an echocardiographic study of a random population sample". Journal of the American College of Cardiology. 21 (5): 1220–5. PMID 8459080. Retrieved 2012-04-10. Unknown parameter
|month=ignored (help) - ↑ Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM (1997). "Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study". Journal of the American College of Cardiology. 29 (3): 630–4. PMID 9060903. Retrieved 2012-04-10. Unknown parameter
|month=ignored (help) - ↑ Otto CM, Lind BK, Kitzman DW, Gersh BJ, Siscovick DS (1999). "Association of aortic-valve sclerosis with cardiovascular mortality and morbidity in the elderly". The New England Journal of Medicine. 341 (3): 142–7. doi:10.1056/NEJM199907153410302. PMID 10403851. Retrieved 2012-04-10. Unknown parameter
|month=ignored (help)