Alagille syndrome laboratory tests: Difference between revisions
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Revision as of 18:30, 17 April 2012
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Alagille syndrome Microchapters |
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Alagille syndrome laboratory tests On the Web |
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Risk calculators and risk factors for Alagille syndrome laboratory tests |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
In addition to various imaging modalities, laboratory tests may be conducted evaluating the bilirubin levels. A liver biopsy may also be conducted on the bile duct to further supplement bilirubin testing.
Laboratory Tests
Biochemical Evaluation
Total Bilirubin >6.5 mg/dL, Conjugated Bilirubin >4.5 mg/dL, and cholesterol >520 mg/dL in children younger than 5 years of age are likely be associated with severe liver disease in later life [1].
Liver Biopsy
A liver biopsy may indicate too few bile ducts (bile duct paucity).
X ray
An unusual butterfly shape of the bones of the spinal column that can be seen in an x-ray
References
- ↑ Kamath BM, Munoz PS, Bab N, Baker A, Chen Z, Spinner NB; et al. (2010). "A longitudinal study to identify laboratory predictors of liver disease outcome in Alagille syndrome". J Pediatr Gastroenterol Nutr. 50 (5): 526–30. doi:10.1097/MPG.0b013e3181cea48d. PMC 2861305. PMID 20421762.