Pulmonary embolism CT: Difference between revisions
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==Overview== | ==Overview== | ||
The traditional gold standard for diagnosing PE is contrast pulmonary angiography. However, invasiveness, its high costs, limited availability and need of an expert radiologist are some of its negative aspects. This chapter deals with the advantages of multidetector CT over CTPA. | |||
==Single Detector CT== | |||
Recent improvement in technology has changed the value of CT angiography for decision making in suspected PE patients. Wide variations regarding both sensitivity (53-100%) and specificity (73-100%) was reported in studies about single detector spiral CT in suspected PE cases.<ref name="pmid10668830">{{cite journal |author=Mullins MD, Becker DM, Hagspiel KD, Philbrick JT |title=The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism |journal=Arch. Intern. Med. |volume=160 |issue=3 |pages=293–8 |year=2000 |month=February |pmid=10668830 |doi= |url=http://archinte.ama-assn.org/cgi/pmidlookup?view=long&pmid=10668830 |accessdate=2012-04-30}}</ref><ref name="pmid10651604">{{cite journal |author=Rathbun SW, Raskob GE, Whitsett TL |title=Sensitivity and specificity of helical computed tomography in the diagnosis of pulmonary embolism: a systematic review |journal=Ann. Intern. Med. |volume=132 |issue=3 |pages=227–32 |year=2000 |month=February |pmid=10651604 |doi= |url=http://www.annals.org/cgi/pmidlookup?view=long&pmid=10651604 |accessdate=2012-04-30}}</ref> | |||
== | Two large multicentric robust clinical studies including more than 1000 patients reported a sensitivity around 70% and a specificity of 90% for single-detector CT.<ref name="pmid11453707">{{cite journal |author=Perrier A, Howarth N, Didier D, Loubeyre P, Unger PF, de Moerloose P, Slosman D, Junod A, Bounameaux H |title=Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism |journal=Ann. Intern. Med. |volume=135 |issue=2 |pages=88–97 |year=2001 |month=July |pmid=11453707 |doi= |url=http://www.annals.org/cgi/pmidlookup?view=long&pmid=11453707 |accessdate=2012-04-30}}</ref><ref name="pmid15634261">{{cite journal |author=Van Strijen MJ, De Monye W, Kieft GJ, Pattynama PM, Prins MH, Huisman MV |title=Accuracy of single-detector spiral CT in the diagnosis of pulmonary embolism: a prospective multicenter cohort study of consecutive patients with abnormal perfusion scintigraphy |journal=J. Thromb. Haemost. |volume=3 |issue=1 |pages=17–25 |year=2005 |month=January |pmid=15634261 |doi=10.1111/j.1538-7836.2004.01064.x |url=http://dx.doi.org/10.1111/j.1538-7836.2004.01064.x |accessdate=2012-04-30}}</ref> | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 23:19, 30 April 2012
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Pulmonary Embolism Microchapters |
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Pulmonary Embolism Assessment of Probability of Subsequent VTE and Risk Scores |
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Pulmonary embolism CT On the Web |
Editor(s)-In-Chief: The APEX Trial Investigators, C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
The traditional gold standard for diagnosing PE is contrast pulmonary angiography. However, invasiveness, its high costs, limited availability and need of an expert radiologist are some of its negative aspects. This chapter deals with the advantages of multidetector CT over CTPA.
Single Detector CT
Recent improvement in technology has changed the value of CT angiography for decision making in suspected PE patients. Wide variations regarding both sensitivity (53-100%) and specificity (73-100%) was reported in studies about single detector spiral CT in suspected PE cases.[1][2]
Two large multicentric robust clinical studies including more than 1000 patients reported a sensitivity around 70% and a specificity of 90% for single-detector CT.[3][4]
References
- ↑ Mullins MD, Becker DM, Hagspiel KD, Philbrick JT (2000). "The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism". Arch. Intern. Med. 160 (3): 293–8. PMID 10668830. Retrieved 2012-04-30. Unknown parameter
|month=ignored (help) - ↑ Rathbun SW, Raskob GE, Whitsett TL (2000). "Sensitivity and specificity of helical computed tomography in the diagnosis of pulmonary embolism: a systematic review". Ann. Intern. Med. 132 (3): 227–32. PMID 10651604. Retrieved 2012-04-30. Unknown parameter
|month=ignored (help) - ↑ Perrier A, Howarth N, Didier D, Loubeyre P, Unger PF, de Moerloose P, Slosman D, Junod A, Bounameaux H (2001). "Performance of helical computed tomography in unselected outpatients with suspected pulmonary embolism". Ann. Intern. Med. 135 (2): 88–97. PMID 11453707. Retrieved 2012-04-30. Unknown parameter
|month=ignored (help) - ↑ Van Strijen MJ, De Monye W, Kieft GJ, Pattynama PM, Prins MH, Huisman MV (2005). "Accuracy of single-detector spiral CT in the diagnosis of pulmonary embolism: a prospective multicenter cohort study of consecutive patients with abnormal perfusion scintigraphy". J. Thromb. Haemost. 3 (1): 17–25. doi:10.1111/j.1538-7836.2004.01064.x. PMID 15634261. Retrieved 2012-04-30. Unknown parameter
|month=ignored (help)