Deep vein thrombosis screening: Difference between revisions
Jump to navigation
Jump to search
Kashish Goel (talk | contribs) No edit summary |
Kashish Goel (talk | contribs) No edit summary |
||
| Line 9: | Line 9: | ||
Screening for inherited thrombophilia in patients who have [[DVT]] is discussed [[Thrombophilia#Laboratory testing|here]]. | Screening for inherited thrombophilia in patients who have [[DVT]] is discussed [[Thrombophilia#Laboratory testing|here]]. | ||
==Pre-test probability== | |||
In a patient with suspected [[DVT]], establishing pre-test probability helps in early risk stratification and appropriate use of laboratory tests and imaging modalities. | In a patient with suspected [[DVT]], establishing pre-test probability helps in early risk stratification and appropriate use of laboratory tests and imaging modalities. | ||
===Wells Score=== | |||
Wells score is the most widely used tool to assess pre-test probability. It includes 10 clinical questions and can range from -2 to 9. | Wells score is the most widely used tool to assess pre-test probability. It includes 10 clinical questions and can range from -2 to 9. | ||
| Line 56: | Line 56: | ||
* Moderate probability: 1-2 | * Moderate probability: 1-2 | ||
* Low probability: ≤ 0 | * Low probability: ≤ 0 | ||
Another scoring system indicates likely (≥ 2) or unlikely (< 2) based on the score of 2. | |||
==References== | |||
{{reflist|2}} | |||
[[Category:Hematology]] | [[Category:Hematology]] | ||
| Line 64: | Line 68: | ||
[[Category:Cardiology]] | [[Category:Cardiology]] | ||
[[Category:Emergency medicine]] | [[Category:Emergency medicine]] | ||
Revision as of 15:23, 14 May 2012
|
Deep Vein Thrombosis Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Special Scenario |
|
Trials |
|
Case Studies |
|
Deep vein thrombosis screening On the Web |
|
Risk calculators and risk factors for Deep vein thrombosis screening |
Overview: Value of screening
In-spite of identifying patients at increased risk of VTE, there is no clear clinical value for screening the general population because:
- The strongest risk factor for VTE recurrence is a prior VTE event itself.
- VTE patients with unknown cause have a high rate of recurrence, after discontinuation of warfarin, irrespective of the presence of inherited thrombophilia.
- Anticoagulant prophylaxis is rarely recommended in asymptomatic affected family members, outside of high risk situations.
Who should be screened?
Screening for inherited thrombophilia in patients who have DVT is discussed here.
Pre-test probability
In a patient with suspected DVT, establishing pre-test probability helps in early risk stratification and appropriate use of laboratory tests and imaging modalities.
Wells Score
Wells score is the most widely used tool to assess pre-test probability. It includes 10 clinical questions and can range from -2 to 9.
| Variable | Wells[1][2] |
|---|---|
| Active cancer (treatment within last 6 months or palliative) | 1 |
| Calf swelling >3 cm compared to other calf (measured 10 cm below tibial tuberosity) | 1 |
| Collateral superficial veins (non-varicose) | 1 |
| Pitting edema (confined to symptomatic leg) | 1 |
| Swelling of entire leg | 1 |
| Localized pain along distribution of deep venous system | 1 |
| Paralysis, paresis, or recent cast immobilization of lower extremities | 1 |
| Recently bedridden > 3 days, or major surgery requiring regional or general anesthetic in past 12 weeks | 1 |
| Previously documented DVT | 1 |
| Alternative diagnosis at least as likely | - 2 |
Interpretation
- High probability: ≥ 3
- Moderate probability: 1-2
- Low probability: ≤ 0
Another scoring system indicates likely (≥ 2) or unlikely (< 2) based on the score of 2.
References
- ↑ Wells PS, Anderson DR, Bormanis J; et al. (1997). "Value of assessment of pretest probability of deep-vein thrombosis in clinical management". Lancet. 350 (9094): 1795–8. doi:10.1016/S0140-6736(97)08140-3. PMID 9428249.
- ↑ Wells PS, Anderson DR, Rodger M; et al. (2003). "Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis". N. Engl. J. Med. 349 (13): 1227–35. doi:10.1056/NEJMoa023153. PMID 14507948. Unknown parameter
|month=ignored (help)