Squamous cell carcinoma of the skin differential diagnosis: Difference between revisions
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The following are the few conditions that mimic [[Squamous cell carcinoma]] | The following are the few conditions that mimic [[Squamous cell carcinoma]] | ||
* [[Actinic Keratosis]] | * [[Actinic Keratosis]] (also called '''solar keratosis''', or '''AK''') is a [[premalignant condition]] of thick, scaly, or crusty patches of skin. It is most common in fair-skinned people who are frequently exposed to the sun, because their pigment isn't very protective. It usually is accompanied by solar damage. Since some of these pre-cancers progress to [[squamous cell carcinoma]], they should be treated. | ||
* [[Atopic Dermatitis]] | * [[Atopic Dermatitis]] | ||
* [[Atypical Fibroxanthoma]] is a tumor that occurs primarily in older individuals when the skin of their head and neck area is exposed to sun and/or therapeutic radiation. Clinically, lesions usually are suggestive of malignancy because they arise rapidly in skin in which other skin cancers have been found and treated. Clinical presentation is a red, beefy, sessile nodule.Solar telangiectasias can be found around the lesions. | * [[Atypical Fibroxanthoma]] is a tumor that occurs primarily in older individuals when the skin of their head and neck area is exposed to sun and/or therapeutic radiation. Clinically, lesions usually are suggestive of malignancy because they arise rapidly in skin in which other skin cancers have been found and treated. Clinical presentation is a red, beefy, sessile nodule.Solar telangiectasias can be found around the lesions. |
Revision as of 05:27, 18 June 2012
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Differentiating Squamous cell carcinoma of the skin from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2], Raviteja Guddeti, M.B.B.S. [3]
Overview
Squamous cell carcinoma is a form of non-melanoma skin tumor. It accounts for 20% of all non-melanoma tumors and is invasive in nature than its counter part Basal cell carcinoma. Initial presentation of Squamous cell carcinoma typically includes a history of a non-healing ulcer or a tumorous growth on the sun exposed areas of the skin of the patients.
Differential Diagnosis
The following are the few conditions that mimic Squamous cell carcinoma
- Actinic Keratosis (also called solar keratosis, or AK) is a premalignant condition of thick, scaly, or crusty patches of skin. It is most common in fair-skinned people who are frequently exposed to the sun, because their pigment isn't very protective. It usually is accompanied by solar damage. Since some of these pre-cancers progress to squamous cell carcinoma, they should be treated.
- Atopic Dermatitis
- Atypical Fibroxanthoma is a tumor that occurs primarily in older individuals when the skin of their head and neck area is exposed to sun and/or therapeutic radiation. Clinically, lesions usually are suggestive of malignancy because they arise rapidly in skin in which other skin cancers have been found and treated. Clinical presentation is a red, beefy, sessile nodule.Solar telangiectasias can be found around the lesions.
- Bowenoid Papulosis presents as papules on the genitalia of both the sexes and is induced virally by the HPV. Many of these lesions are benign but there are case reports of malignant transformation (2.6%).
- Contact Dermatitis
- Erythroplasia of Queyrat
- Keratoacanthoma is a low-grade malignancy of the skin. It originates in the pilo-sebaceous glands, and is similar in clinical presentation and microscopic analysis to squamous cell carcinoma, except that it contains a central keratin plug. Statistically, it is less likely to become invasive than squamous cell carcinoma.
- Bowen's disease is a sunlight-induced skin disease, and is considered to be an early form of squamous cell carcinoma.
- Marjolin's ulcer is a type of squamous cell carcinoma that arises from a non-healing ulcer or burn wound.
- Melanoma
- Basal Cell Carcinoma
- Pyoderma Gangrenosum is an uncommon ulcerative condition associated with systemic disease in at least 50% of the cases. This condition is a diagnosis of exclusion.
References