Macroglossia

Macroglossia
ICD-10	Q38.2
ICD-9	529.8
OMIM	153630
DiseasesDB	7689
MeSH	D008260

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Overview

Macroglossia is the medical term for unusual enlargement (hypertrophy) of the tongue. Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping.

Causes

Macroglossia is a feature of the following disorders:

• Acromegaly
• Amyloidosis (in primary and myeloma-related)
• Beckwith-Wiedemann syndrome
• Congenital hypothyroidism
• Hurler syndrome
• Immunodeficiency, centromere instability and facial anomalies syndrome