Familial Eosinophilic Cellulitis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Also called Wells syndrome is a rare eosinophilic disorder characterized by itchy, burning, red, and inflamed areas on the skin often on the lower arm or leg. The lesions may be single or multiple. They are usually red at first (looking like cellulitis) then change to brown red, to blue gray, then greenish gray. The lesions are usually painful and are sometimes associated with a fever. They typically heal without scarring within weeks to months; however they often recur. The cause of Wells syndrome is unknown; but some researchers think that Wells syndrome is anautoimmune reaction.