Encephalopathy pathophysiology: Difference between revisions
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'''Hepatic encephalopathy''' | '''Hepatic encephalopathy''' | ||
Brain is protected from the circulatory toxins by blood brain barrier lined by astrocytes. In cases of hepatic failure due to any reason, detoxifying capacity of liver is drastically reduced. This causes increase in concentration of circulatory toxins like ammonia, mercaptans, manganese. Circulatory toxins damage the barrier made by astrocytes and cause pathological changes in the cells. This alters blood brain barrier and toxins gain access into the brain tissues. | Brain is protected from the circulatory toxins by blood brain barrier lined by astrocytes. In cases of hepatic failure due to any reason, detoxifying capacity of liver is drastically reduced. This causes increase in concentration of circulatory toxins like ammonia, mercaptans, manganese. Circulatory toxins damage the barrier made by astrocytes and cause pathological changes in the cells. This alters blood brain barrier and toxins gain access into the brain tissues. | ||
'''Hypoxic encephalopahty''' | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 03:09, 20 July 2012
Encephalopathy |
Diagnosis |
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Treatment |
Encephalopathy pathophysiology On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Pathophysiology
Encephalopathy is a broad term given to lots of condition's which cause dysfunction of brain. There are varied ways of causing encephalopthies.
Hepatic encephalopathy Brain is protected from the circulatory toxins by blood brain barrier lined by astrocytes. In cases of hepatic failure due to any reason, detoxifying capacity of liver is drastically reduced. This causes increase in concentration of circulatory toxins like ammonia, mercaptans, manganese. Circulatory toxins damage the barrier made by astrocytes and cause pathological changes in the cells. This alters blood brain barrier and toxins gain access into the brain tissues.
Hypoxic encephalopahty