Encephalopathy MRI: Difference between revisions

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* Increased signal sensitivity in globus pallidus on T1 weighted images.<ref name="pmid1446893">{{cite journal |author=Kulisevsky J, Pujol J, Balanzó J, ''et al.'' |title=Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations |journal=Hepatology |volume=16 |issue=6 |pages=1382–8 |year=1992 |month=December |pmid=1446893 |doi= |url=}}</ref>
* Increased signal sensitivity in globus pallidus on T1 weighted images.<ref name="pmid1446893">{{cite journal |author=Kulisevsky J, Pujol J, Balanzó J, ''et al.'' |title=Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations |journal=Hepatology |volume=16 |issue=6 |pages=1382–8 |year=1992 |month=December |pmid=1446893 |doi= |url=}}</ref>
* This intensity may be due to accumulation of manganese<ref name="pmid7630246">{{cite journal |author=Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H |title=Manganese and chronic hepatic encephalopathy |journal=Lancet |volume=346 |issue=8970 |pages=270–4 |year=1995 |month=July |pmid=7630246 |doi= |url=}}</ref>
* This intensity may be due to accumulation of manganese<ref name="pmid7630246">{{cite journal |author=Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H |title=Manganese and chronic hepatic encephalopathy |journal=Lancet |volume=346 |issue=8970 |pages=270–4 |year=1995 |month=July |pmid=7630246 |doi= |url=}}</ref>
==Magnetic Resonance Spectroscopy (MRS)==
* Non invasive method which allows serial measurement of various neuro metabolites in brain.
* Patients of hepatic encephalopathy show increase in glutamate.
* MRI and MRS are correlated with other brain lesions like parkinson's disease.  It helps in differentiating from encephalopathy.


==References==
==References==

Revision as of 20:43, 22 July 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

More effective than CT scan in identifying lesions. Useful in differentiating the hepatic encephalopathy from the underlying brain causes. Increased resonance in T1 weighted images in hepatic encephalopathy due to manganese.[1]

MRI Scan

  • More effective than CT scan in identifying lesions
  • Useful in differentiating the hepatic encephalopathy from the underlying brain causes.
  • Increased signal sensitivity in globus pallidus on T1 weighted images.[2]
  • This intensity may be due to accumulation of manganese[1]

Magnetic Resonance Spectroscopy (MRS)

  • Non invasive method which allows serial measurement of various neuro metabolites in brain.
  • Patients of hepatic encephalopathy show increase in glutamate.
  • MRI and MRS are correlated with other brain lesions like parkinson's disease. It helps in differentiating from encephalopathy.

References

  1. 1.0 1.1 Krieger D, Krieger S, Jansen O, Gass P, Theilmann L, Lichtnecker H (1995). "Manganese and chronic hepatic encephalopathy". Lancet. 346 (8970): 270–4. PMID 7630246. Unknown parameter |month= ignored (help)
  2. Kulisevsky J, Pujol J, Balanzó J; et al. (1992). "Pallidal hyperintensity on magnetic resonance imaging in cirrhotic patients: clinical correlations". Hepatology. 16 (6): 1382–8. PMID 1446893. Unknown parameter |month= ignored (help)

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