Multiple myeloma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

MRI

The workup of suspected multiple myeloma includes a skeletal survey. This is a series of X-rays of the skull, axial skeleton and proximal long bones. Myeloma activity sometimes appear as "lytic lesions" (with local disappearance of normal bone due to resorption), and on the skull X-ray as "punched-out lesions" (pepper pot skull). Magnetic resonance imaging (MRI) is more sensitive than simple X-ray in the detection of lytic lesions, and may supersede skeletal survey, especially when vertebral disease is suspected. Occasionally a CT scan is performed to measure the size of soft tissue plasmacytomas.

(Images courtesy of RadsWiki)

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  Multiple myeloma
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  Multiple myeloma
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  Multiple myeloma

Back pain in a patient with known multiple myeloma

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