Chagas disease overview: Difference between revisions

Jump to navigation Jump to search
Daniel Nethala (talk | contribs)
Undo revision 648317 by Daniel Nethala (talk)
Raviteja Reddy Guddeti (talk | contribs)
No edit summary
Line 1: Line 1:
Chagas disease is a pathogenic tropical disease transmitted by the protozoa, ''[[Trypanosoma cruzi]]''. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal.
__NOTOC__
{{SI}}
{{CMG}}; {{AE}} {{RT}}
 
==Overview==
 
Chagas disease is a pathogenic tropical disease transmitted by the [[protozoa]], ''[[Trypanosoma cruzi]]''. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal.
{{#widget:SchemaSnippet}}
{{#widget:SchemaSnippet}}
==Background==
==Background==
'''Chagas' disease''' (also called '''''[[American trypanosomiasis]]''''' or '''''[[Trypanosoma cruzi Infection]]''''') is a human [[tropical disease|tropical]] [[parasitic disease]] which occurs in the Americas, particularly in South America. Its [[pathogen]]ic [[Vector (biology)|agent]] is a [[flagellate]] [[protozoa]]n named ''[[Trypanosoma cruzi]]'', which is transmitted to humans and other [[mammal]]s mostly by [[hematophagy|blood-sucking]] [[assassin bug]]s of the subfamily [[Triatominae]] (Family [[Reduviidae]]). Those insects are known by numerous common names varying by country, including benchuca, vinchuca, kissing bug, chipo, chupança and barbeiro. The most common insect species belong to the genera ''[[Triatoma]]'', ''[[Rhodnius]]'', and ''[[Panstrongylus]]''. Other forms of transmission are possible, though, such as ingestion of food contaminated with [[parasite]]s, [[blood transfusion]] and [[fetus|fetal]] transmission.
'''Chagas' disease''' (also called '''''[[American trypanosomiasis]]''''' or '''''[[Trypanosoma cruzi Infection]]''''') is a human [[tropical disease|tropical]] [[parasitic disease]] which occurs in the Americas, particularly in South America. Its [[pathogen]]ic [[Vector (biology)|agent]] is a [[flagellate]] [[protozoa]]n named ''[[Trypanosoma cruzi]]'', which is transmitted to humans and other [[mammal]]s mostly by [[hematophagy|blood-sucking]] [[assassin bug]]s of the subfamily [[Triatominae]] (Family [[Reduviidae]]). Those insects are known by numerous common names varying by country, including benchuca, vinchuca, kissing bug, chipo, chupança and barbeiro. The most common insect species belong to the genera ''[[Triatoma]]'', ''[[Rhodnius]]'', and ''[[Panstrongylus]]''. Other forms of transmission are possible, though, such as ingestion of food contaminated with [[parasite]]s, [[blood transfusion]] and [[fetus|fetal]] transmission.


The symptoms of Chagas' disease vary over the course of the infection. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal. Current drug treatments for this disease are generally unsatisfactory, with the available drugs being highly toxic and often ineffective, particularly in the chronic stage of the disease.
The symptoms of Chagas' disease vary over the course of the infection. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal. Current drug treatments for this disease are generally unsatisfactory, with the available drugs being highly toxic and often ineffective, particularly in the chronic stage of the disease.


''Trypanosoma cruzi'' is a member of the same [[genus]] as the infectious agent of African [[sleeping sickness]] and the same [[Order (biology)|order]] as the infectious agent of [[leishmaniasis]], but its clinical manifestations, geographical distribution, life cycle and insect [[vector (biology)|vectors]] are quite different.
''Trypanosoma cruzi'' is a member of the same [[genus]] as the infectious agent of African [[sleeping sickness]] and the same [[Order (biology)|order]] as the infectious agent of [[leishmaniasis]], but its clinical manifestations, geographical distribution, life cycle and insect [[vector (biology)|vectors]] are quite different.
Line 10: Line 16:
==References==
==References==
{{Reflist|2}}
{{Reflist|2}}
{{WH}}
{{WS}}

Revision as of 19:53, 6 August 2012

WikiDoc Resources for Chagas disease overview

Articles

Most recent articles on Chagas disease overview

Most cited articles on Chagas disease overview

Review articles on Chagas disease overview

Articles on Chagas disease overview in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Chagas disease overview

Images of Chagas disease overview

Photos of Chagas disease overview

Podcasts & MP3s on Chagas disease overview

Videos on Chagas disease overview

Evidence Based Medicine

Cochrane Collaboration on Chagas disease overview

Bandolier on Chagas disease overview

TRIP on Chagas disease overview

Clinical Trials

Ongoing Trials on Chagas disease overview at Clinical Trials.gov

Trial results on Chagas disease overview

Clinical Trials on Chagas disease overview at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Chagas disease overview

NICE Guidance on Chagas disease overview

NHS PRODIGY Guidance

FDA on Chagas disease overview

CDC on Chagas disease overview

Books

Books on Chagas disease overview

News

Chagas disease overview in the news

Be alerted to news on Chagas disease overview

News trends on Chagas disease overview

Commentary

Blogs on Chagas disease overview

Definitions

Definitions of Chagas disease overview

Patient Resources / Community

Patient resources on Chagas disease overview

Discussion groups on Chagas disease overview

Patient Handouts on Chagas disease overview

Directions to Hospitals Treating Chagas disease overview

Risk calculators and risk factors for Chagas disease overview

Healthcare Provider Resources

Symptoms of Chagas disease overview

Causes & Risk Factors for Chagas disease overview

Diagnostic studies for Chagas disease overview

Treatment of Chagas disease overview

Continuing Medical Education (CME)

CME Programs on Chagas disease overview

International

Chagas disease overview en Espanol

Chagas disease overview en Francais

Business

Chagas disease overview in the Marketplace

Patents on Chagas disease overview

Experimental / Informatics

List of terms related to Chagas disease overview

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Chagas disease is a pathogenic tropical disease transmitted by the protozoa, Trypanosoma cruzi. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal.

Background

Chagas' disease (also called American trypanosomiasis or Trypanosoma cruzi Infection) is a human tropical parasitic disease which occurs in the Americas, particularly in South America. Its pathogenic agent is a flagellate protozoan named Trypanosoma cruzi, which is transmitted to humans and other mammals mostly by blood-sucking assassin bugs of the subfamily Triatominae (Family Reduviidae). Those insects are known by numerous common names varying by country, including benchuca, vinchuca, kissing bug, chipo, chupança and barbeiro. The most common insect species belong to the genera Triatoma, Rhodnius, and Panstrongylus. Other forms of transmission are possible, though, such as ingestion of food contaminated with parasites, blood transfusion and fetal transmission.

The symptoms of Chagas' disease vary over the course of the infection. In the early, acute stage symptoms are mild and are usually no more than local swelling at the site of infection. As the disease progresses, over as much as twenty years, the serious chronic symptoms appear, such as heart disease and malformation of the intestines. If untreated, the chronic disease is often fatal. Current drug treatments for this disease are generally unsatisfactory, with the available drugs being highly toxic and often ineffective, particularly in the chronic stage of the disease.

Trypanosoma cruzi is a member of the same genus as the infectious agent of African sleeping sickness and the same order as the infectious agent of leishmaniasis, but its clinical manifestations, geographical distribution, life cycle and insect vectors are quite different.

References


Template:WH Template:WS

Cookies help us deliver our services. By using our services, you agree to our use of cookies.

Navigation menu