Psittacosis laboratory tests: Difference between revisions
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* Urinalysis may show proteinuria | * Urinalysis may show proteinuria | ||
===Biopsy=== | ===Biopsy=== | ||
* Macroscopically they have patchy consolidation. | * Macroscopically they have patchy consolidation. |
Revision as of 19:07, 7 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Exposure history is paramout to diagnosis. Bloodwork shows leukopenia, thrombocytopenia and moderately elevated liver enzymes.
Laboratory Findings
Electrolyte and Biomarker Studies
- Leukocytosis
- Rise in ESR
- Rise in CRP
- Liver enzymes elevated
- Hyponatremia may be noticed
- Rise in blood urea levels
- Urinalysis may show proteinuria
Biopsy
- Macroscopically they have patchy consolidation.
- Microscopically exudation and interstitial changes are seen.
- They are best seen with Giemsa stain as inclusions called Leventhal -Colle-Lillie bodies and can be seen within macrophages in BAL fluid.
Culture
- Microbiological cultures from respiratory secretions.
- Culture of Chlamydia psittaci is hazardous and should only be carried out in biosafety laboratories.
- It is tedious process and seldom done .
Serology
- A fourfold or greater increase in antibody titers are against the diagnosis of C. psittaci in blood samples combined with the probable course of the disease.