CYP4F22: Difference between revisions
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'''CYP4F22''' ('''cy'''tochrome '''P'''450, family '''4''', subfamily '''F''', polypeptide '''22''') is a [[protein]] which in humans is encoded by the ''CYP4F22'' [[gene]].<ref name="pmid16436457">{{cite journal | author = Lefèvre C, Bouadjar B, Ferrand V, Tadini G, Mégarbané A, Lathrop M, Prud'homme JF, Fischer J | title = Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3 | journal = Hum. Mol. Genet. | volume = 15 | issue = 5 | pages = 767–76 | year = 2006 | month = March | pmid = 16436457 | doi = 10.1093/hmg/ddi491 | url = | issn = }}</ref> | '''CYP4F22''' ('''cy'''tochrome '''P'''450, family '''4''', subfamily '''F''', polypeptide '''22''') is a [[protein]] which in humans is encoded by the ''CYP4F22'' [[gene]].<ref name="pmid16436457">{{cite journal | author = Lefèvre C, Bouadjar B, Ferrand V, Tadini G, Mégarbané A, Lathrop M, Prud'homme JF, Fischer J | title = Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3 | journal = Hum. Mol. Genet. | volume = 15 | issue = 5 | pages = 767–76 | year = 2006 | month = March | pmid = 16436457 | doi = 10.1093/hmg/ddi491 | url = | issn = }}</ref> | ||
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Revision as of 23:20, 8 August 2012
| cytochrome P450, family 4, subfamily F, polypeptide 22 | |
|---|---|
| Identifiers | |
| Symbol | CYP4F22 |
| Entrez | 126410 |
| HUGO | 26820 |
| OMIM | 611495 |
| RefSeq | NM_173483 |
| UniProt | Q6NT55 |
| Other data | |
| Locus | Chr. 19 p13.12 |
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CYP4F22 (cytochrome P450, family 4, subfamily F, polypeptide 22) is a protein which in humans is encoded by the CYP4F22 gene.[1]
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This gene is part of a cluster of cytochrome P450 genes on chromosome 19 and encodes an enzyme thought to play a role in the 12(R)-lipoxygenase pathway. Mutations in this gene are the cause of ichthyosis lamellar type 3.[2]
References
- ↑ Lefèvre C, Bouadjar B, Ferrand V, Tadini G, Mégarbané A, Lathrop M, Prud'homme JF, Fischer J (2006). "Mutations in a new cytochrome P450 gene in lamellar ichthyosis type 3". Hum. Mol. Genet. 15 (5): 767–76. doi:10.1093/hmg/ddi491. PMID 16436457. Unknown parameter
|month=ignored (help) - ↑ "Entrez Gene: CYP4F22".
This article incorporates text from the United States National Library of Medicine, which is in the public domain.