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'''Calcium carbimide''', sold as the [[citrate]] [[salt (chemistry)|salt]] under the trade name '''Temposil''', is an [[alcohol]] sensitizing agent. Its effects are similar to the drug [[disulfiram]] (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic byproduct [[acetaldehyde]]. The result is that when alcohol is consumed by users of calcium carbimide, they experience severe reactions which include symptoms such as sweating, difficulty breathing, rapid heartbeat, rash, nausea and vomiting, and headache.
'''Calcium carbimide''', sold as the [[citrate]] [[salt (chemistry)|salt]] under the trade name '''Temposil''', is an [[alcohol]] sensitizing agent. Its effects are similar to the drug [[disulfiram]] (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic byproduct [[acetaldehyde]]. The result is that when alcohol is consumed by users of calcium carbimide, they experience severe reactions which include symptoms such as sweating, difficulty breathing, rapid heartbeat, rash, nausea and vomiting, and headache.

Revision as of 23:21, 8 August 2012

Calcium carbimide
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
FormulaC6H8O7.CH2N2.Ca
Molar mass288.268 g/mol


Calcium carbimide, sold as the citrate salt under the trade name Temposil, is an alcohol sensitizing agent. Its effects are similar to the drug disulfiram (Antabuse) in that it interferes with the normal metabolism of alcohol by preventing the breakdown of the metabolic byproduct acetaldehyde. The result is that when alcohol is consumed by users of calcium carbimide, they experience severe reactions which include symptoms such as sweating, difficulty breathing, rapid heartbeat, rash, nausea and vomiting, and headache.

While calcium carbimide is a good adjunct to other treatments for alcoholism, it has been found that, as with Antabuse, it is an ineffective therapy on its own, and many alcoholics will voluntarily discontinue the drug in order to continue drinking.

Template:Drugs used in addictive disorders

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