Cefradine

Cefradine

Clinical data
Routes of administration	Oral, IM, IV
ATC code	J01DB09 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability	Well absorbed
Protein binding	<10%
Metabolism	Nil
Elimination half-life	0.9 hours
Excretion	Renal, unchanged
Identifiers
IUPAC name (6R,7R)-7-{[(2R)-2-amino-2-(1-cyclohexa-1,4- dienyl)acetyl]amino}-3-methyl-8-oxo-5-thia- 1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number	38821-53-3
PubChem CID	38103
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C16H19N3O4S
Molar mass	349.406 g/mol

WikiDoc Resources for Cefradine
Articles
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Evidence Based Medicine
Cochrane Collaboration on Cefradine Bandolier on Cefradine TRIP on Cefradine
Clinical Trials
Ongoing Trials on Cefradine at Clinical Trials.gov Trial results on Cefradine Clinical Trials on Cefradine at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Cefradine NICE Guidance on Cefradine NHS PRODIGY Guidance FDA on Cefradine CDC on Cefradine
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Commentary
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Definitions
Definitions of Cefradine
Patient Resources / Community
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Healthcare Provider Resources
Symptoms of Cefradine Causes & Risk Factors for Cefradine Diagnostic studies for Cefradine Treatment of Cefradine
Continuing Medical Education (CME)
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International
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Experimental / Informatics
List of terms related to Cefradine

Overview

Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic.

Indications

It has similar spectrum of activity to cefalexin.

Dosage

Dosage by mouth for adults is 250–500 mg every 6 hours, or 500 mg to 1 g every 12 hours. In severe infections up to 1 g every 6 hours may be used. Dosages for children are based upon their weight with 25–50 mg/kg total daily dose given in 2–4 divided doses.

Formulations

Caspules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

• British National Formulary 45 March 2003