DAMGO: Difference between revisions
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Revision as of 00:26, 9 August 2012
Template:Chembox new Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
DAMGO ([D-Ala2, N-MePhe4, Gly-ol]-enkephalin) is a synthetic opioid peptide with high μ-opioid receptor specificity. It was synthesized as a biologically stable analog of δ-opioid receptor-preferring endogenous opioids, leu- and met-enkephalin.[1]
Its structure is H-Tyr-D-Ala-Gly-N-MePhe-Gly-OH.
References
- ↑ Handa BK, Land AC, Lord JA, Morgan BA, Rance MJ, Smith CF. "Analogues of β-LPH61–64 possessing selective agonist activity at μ-opiate receptors." European Journal of Pharmacology. 1981 Apr 9;70(4):531-40. PMID 6263640. doi:10.1016/0014-2999(81)90364-2