Metalloestrogen: Difference between revisions
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'''Metalloestrogens''' are a class of [[inorganic]] [[xenoestrogen]]s which can affect the gene expression of human cells responding to [[estrogen]]. Effects are related to the physiologic function of estrogen because metalloestrogens have shown [[affinity]] for [[estrogen receptor]]s. Because they can mimic estrogen thus activating the receptor, they are considered harmful and potentially linked with [[breast cancer]].<ref>[http://www3.interscience.wiley.com/cgi-bin/abstract/112438172/ABSTRACT Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast] J Appl Toxicol. 2006 May-Jun;26(3):191-7.</ref> List of metalloestrogens include [[aluminium]], [[antimony]], [[arsenite]], [[barium]], [[cadmium]], [[chromium]] (Cr(II)), [[cobalt]], [[copper]], [[lead]], [[mercury (element)|mercury]], [[nickel]], [[selenite]], [[tin]] and [[vanadate]]. | '''Metalloestrogens''' are a class of [[inorganic]] [[xenoestrogen]]s which can affect the gene expression of human cells responding to [[estrogen]]. Effects are related to the physiologic function of estrogen because metalloestrogens have shown [[affinity]] for [[estrogen receptor]]s. Because they can mimic estrogen thus activating the receptor, they are considered harmful and potentially linked with [[breast cancer]].<ref>[http://www3.interscience.wiley.com/cgi-bin/abstract/112438172/ABSTRACT Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast] J Appl Toxicol. 2006 May-Jun;26(3):191-7.</ref> List of metalloestrogens include [[aluminium]], [[antimony]], [[arsenite]], [[barium]], [[cadmium]], [[chromium]] (Cr(II)), [[cobalt]], [[copper]], [[lead]], [[mercury (element)|mercury]], [[nickel]], [[selenite]], [[tin]] and [[vanadate]]. | ||
==References== | ==References== | ||
{{reflist}} | {{reflist}} | ||
[[Category:Estrogens]] | [[Category:Estrogens]] | ||
[[Category:Endocrinology]] | [[Category:Endocrinology]] | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Revision as of 17:21, 9 August 2012
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Metalloestrogens are a class of inorganic xenoestrogens which can affect the gene expression of human cells responding to estrogen. Effects are related to the physiologic function of estrogen because metalloestrogens have shown affinity for estrogen receptors. Because they can mimic estrogen thus activating the receptor, they are considered harmful and potentially linked with breast cancer.[1] List of metalloestrogens include aluminium, antimony, arsenite, barium, cadmium, chromium (Cr(II)), cobalt, copper, lead, mercury, nickel, selenite, tin and vanadate.
References
- ↑ Metalloestrogens: an emerging class of inorganic xenoestrogens with potential to add to the oestrogenic burden of the human breast J Appl Toxicol. 2006 May-Jun;26(3):191-7.