EKG abnormalities in central nervous system disease: Difference between revisions
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{{WikiDoc Cardiology Network Infobox}} | {{WikiDoc Cardiology Network Infobox}} | ||
{{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}} | {{CMG}}; '''Associate Editor-In-Chief:''' {{CZ}} | ||
==Overview== | |||
Classic manifestations on EKG of the so-called CVA (cerebrovascular accident, most commonly associated with subarachnoid hemorrhage or other intracranial bleeds) are deep inverted giant T wave inversion. The mechanisms are not fully delineated but may relate to excessive catecholamine stimulation causing direct myocardial injury. Takostubo syndrome may occur in some cases. The long QT-U may predispose to torsade(s) de pointes. | |||
The ECG may be notable for marked QT-U prolongation (sometimes a giant U wave appears to be appended to the T wave, creating a slight discontinuity in waveform morphology). Apical hypertrophic cardiomyopathy (Yamaguchi’s syndrome) is associated with deep, but relatively narrow (spade-like) T wave inversions, most marked in the mid-precordial leads. | |||
==Electrocardiographic Findings:== | ==Electrocardiographic Findings:== | ||
# EKG changes seen in 71.5% of patients with [[subarachnoid hemorrhage]], and 57.1% of those with [[cerebral hemorrhage]]. | # EKG changes seen in 71.5% of patients with [[subarachnoid hemorrhage]], and 57.1% of those with [[cerebral hemorrhage]]. |
Revision as of 13:55, 11 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Classic manifestations on EKG of the so-called CVA (cerebrovascular accident, most commonly associated with subarachnoid hemorrhage or other intracranial bleeds) are deep inverted giant T wave inversion. The mechanisms are not fully delineated but may relate to excessive catecholamine stimulation causing direct myocardial injury. Takostubo syndrome may occur in some cases. The long QT-U may predispose to torsade(s) de pointes. The ECG may be notable for marked QT-U prolongation (sometimes a giant U wave appears to be appended to the T wave, creating a slight discontinuity in waveform morphology). Apical hypertrophic cardiomyopathy (Yamaguchi’s syndrome) is associated with deep, but relatively narrow (spade-like) T wave inversions, most marked in the mid-precordial leads.
Electrocardiographic Findings:
- EKG changes seen in 71.5% of patients with subarachnoid hemorrhage, and 57.1% of those with cerebral hemorrhage.
- Most common abnormalities are
- Large, upright, or deeply inverted T waves
- Prolongation of the QTc interval
- Prominent U waves
- Can persist for 11 days
- Rarely can ST segment elevation or depression
- Rhythm disturbances
- Reason for changes is thought to be altered autonomic tone
Examples
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Patient with subaracnoidal hemorrhage
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EKG of a patients with CNS Disorders
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Inverted and deep T waves in the precordal leads due to subaracnoidal aneurysm [Image courtesy of Dr Jose Ganseman Dr Ganseman's webpage: An ultimate source of EKG