Drug allergy physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Charmaine Patel, M.D. [2]

Drug Allergy
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Physical Examination

Appearance of the Patient

This will vary depending on the severity of the reaction. Patient may be uncomfortable, itchy, or may just have a very localized area of redness. They may have a rash or lesions that are visible on first glance, and if they are experiencing bronchospasm and a

Skin

• Erythema multiforme (target lesions) may be present
• Erythematous rash that blanches may be present
• Skin may be warm to the touch
• Sloughing of the skin may be present
• Blisters, pustules, and pus may be present
• Nikolsky's sign may be present (in toxic epidermal necrolysis)